prostate-specific antigen (psa) was purified to homogeneity from human seminal plasma by ion-exchange chromatography on a cm-sephadex c-50 and by gel filtration on a sephacryl s-200 column. a single 33-kda protein band appeared in sds-page. high pressure liquid chromatography (hplc) of the purified protein produced a single peak, while isoelectric focusing demonstrated the presence of five diff...

background: the normal prostate-specific antigen (psa) level in patients with urethral catheterization is a controversy. we designed this study to investigate the effect of nontraumatic urethral catheterization without urinary retention on serum psa. materials and methods: seventy patients scheduled for urethral catheterization before elective surgeries were randomly selected and included in th...

background: it is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum psa in iranian population. objective: to determine age-specific reference ranges for serum prostate-specific antigen (psa) concentration and psa density (psad) and prostate volumes in a population of he...

hydatid cyst fluid has been used as a source of antigen for the serodiagnosis of echinococcus granulosus infection. due to cross-reactions with antigens shared by other helminthes, the specific antigen from hydatid cyst fluid was purified by many workers. we used a relatively simple technique for purification of specific antigen from sheep hydatid cyst fluid. isopycnic ultracentrifugation with ...

background defining the optimal prostate-specific antigen threshold to identify the patients at the highest risk of prostate cancer has always been a controversial issue. objectives this study aims to analyze the diagnostic value of psa and also evaluate the relationship between psa (prostate-specific antigen) and bmi (body mass index) as well as psa and prostate size and volume in asymptomatic...

to determine the normal ranges of serum age-related prostate-specific antigen (psa) level in men from beijing area without cancer.in this cross sectional study, form april 2010 to october 2011, 1611 healthy men undergoing a routine health check-up in our hospital and all men received three examinations including serum psa test, digital rectal ex-amination and transrectal ultrasound. men with an...

background and objective: prostate cancer is a prevalent disease around the world. the prostatic specific antigen (psa) test has recently proved itself as a useful method for the diagnosis and examination of patients with prostatic cancer. the objective of this study was to compare the stability of free psa and total psa in different storage settings. materials and methods: samples were obtaine...

background prostate is an important male reproductive system gland and its disorders can affect men's quality of life and health. prostatitis, benign prostatic hyperplasia (bph), and prostate adenocarcinoma are major disorders that can be found in all men in different ages. objectives the aim of this study was to investigate the association of diet with serum prostate specific antigen (psa) lev...

Background: It is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum PSA in Iranian population. Objective: To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and PSA density (PSAD) and prostate volumes in a population of he...

background: nowadays, highly specific aptamers generated by cell selex technology (systematic evolution of ligands by exponential enrichment) are being applied for early detection of cancer cells. prostate specific membrane antigen (psma), over expressed in prostate cancer, is a highly specific marker and therefore can be used for diagnosis of the prostate cancer cells. the aim of the present s...