Although it is established that failure of regulatory mechanisms underlies many autoimmune diseases, the stimuli that activate autoreactive lymphocytes remain poorly understood. Defining these stimuli will lead to therapeutic strategies for autoimmune diseases. IL-2-deficient mice develop spontaneous autoimmunity, because of a deficiency of regulatory T cells, and on the BALB/c background, they...

This is a report on a methodological adaptation of the photogrammetric technique, which is used in other medical specialties, for use in analyzing respiratory movements. Photogrammetry and a model of photogrammetry designated biofotogrametria para análise da mecânica respiratória (BAMER, photogrammetric analysis of respiratory mechanics) were tested under previously described pathophysiological...

background: including multivariate survival data can be pointed competing risks data. there are various methods to analyze such data such as semi-parametric methods of cause-specific hazard function, and cumulative incidence function. the aim of this study was to deploy competing risks model to analyze the determinants of patients with liver cirrhosis. materials and methods: during the one-year...

inventory models play an important role in determining the optimal ordering and pricing policies. much work has been reported in literature regarding inventory models with finite or infinite replenishment. but in many practical situations the replenishment is governed by random factors like procurement, transportation, environmental condition, availability of raw material etc., hence, it is nee...

AIM The purpose of this study is to analyze the cost of GERD and functional dyspepsia for investing its related factors. BACKGROUND Gastro-oesophageal reflux disease GERD and dyspepsia are the most common symptoms of gastrointestinal disorders. Recent studies showed high prevalence and variety of clinical presentation of these two symptoms imposed enormous economic burden to the society. Cost...

Anxiety sensitivity (AS), has been conceptualized as a hierarchical construct, comprising three lowerorder dimensions. Recent findings suggest that AS may be better conceptualized as a general dimension and unrelated physical, cognitive, and social concerns dimensions (a bifactor model). The current study was designed to examine whether a bifactor model best represented AS in a sample of 878 co...