introduction: squamous cell carcinoma (scc) is the most common head and neck malignancy. to decrease the side effects of treatment and mortality from disease relapse, careful staging for the proper treatment plan is necessary. the main purpose of this prospective study is to compare the diagnostic value of computed tomography (ct) and magnetic resonance im-aging (mri) in oral scc and its lymph ...

objective(s) matrix metalloproteinases comprise a family of enzyme that is able to degrade components of extra cellular matrix. there are single nucleotide polymorphisms in the promoter regions of several genes with ability to influence cancer susceptibility. the aim of this study was to analyses association between mmp2 and mmp9 promoter polymorphisms and head and neck squamous cell carcinoma ...

verrucous carcinoma is a unique clinical and pathological entity which has been recognised in the recent years. it is a variant of well-differentiated squamous cell carcinoma which may occur in the larynx; other anatomic locations such as: the oral cavity, anogenital region, and skin may be involved. it accounts for 1-2% of all laryngeal cancers. the clinical, histopathological and biologic fea...

marjolin's ulcer following frostbite is a rare occurrence. our review of literature revealed that only 23 cases have been reported. in most instances heel is involved and the most common associated malignancy is squamous cell carcinoma. we present a 69-year-old male patient with squamous cell carcinoma arising over a frostbite scar in heel 45 years after cold injury. this case is unique with re...

background & objective: chronic non healing ulcers or scar undergoing malignant transformation is a rare phenomenon with an estimated incidence of 2%. though, numerous predisposing factors have been identified, still it is rarely diagnosed and commonly mistaken for a benign condition. the objective of this study was to verify the efficacy of the fine needle aspiration cytology/ scrape cytol...

"Muir-Torre syndrome, a subtype of Lynch is rare genetic disorder. We present the case female patient with long family and personal history who was diagnosed numerous benign malignant tumours various histology, including some sebaceous features, beginning at age 41. The majority were cutaneous tumours, treated complete resection, but they frequently recurred. Visceral cancers included endocervi...

Background: Although the imbalance of cytokines in Head and Neck Squamous Cell Carcinoma (HNSCC) is well known, there is scarce data regarding its occurrence during dysplasia, before the malignant transformation. Objective: To determine whether laryngeal dysplasia patients show a different cytokine profile than patients with cancer and healthy controls. Methods: Seventeen newly diagnosed, untre...