OBJECTIVE To investigate whether salvage radiation therapy (SRT) may promote prostate cancer (PCa) transformation to more aggressive phenotypes. To accomplish that, we identified men who underwent SRT after radical prostatectomy for PCa and failed SRT. PSA doubling time (PSADT) was used as a surrogate endpoint for cancer aggressiveness. We compared PSADT calculated before start of SRT and after...

objectives: this study aimed to evaluate the psychometric properties of the srt that was performed in 4-6 year-old persian-speaking children. the srt is a nonword repetition task that assesses phonological working memory and was designed by shriberg in 2008. methods: the present research was a non-experimental study with a methodological design. the content validity of the task was evaluated by...

background: the pneumatic tourniquet (pt) is routinely used in upper and lower limb operations by most orthopaedic surgeons. the silicone ring tourniquet (srt) was introduced in clinical practice the last decade. clinical as well comparative studies in volunteers concerning its safety and efficacy have been published. the aim of this study was to investigate the postoperative effect of the sili...

BACKGROUND AND PURPOSE In a retrospective analysis, we examined factors influencing the outcome of prostate cancer (PCa) patients receiving salvage radiotherapy (SRT) for PSA recurrence after radical prostatectomy (RP). MATERIAL AND METHODS 306 patients received 3D-conformal SRT at a median pre-SRT PSA of 0.298 ng/ml. Post-SRT progression was defined as PSA ⩾0.2 ng/ml above nadir and rising f...

Prostate cancer is the second most common cause of cancer death in American men. What to do when prostate cancer recurs months or years after a patient undergoes radical prostatectomy is an area of active research. Patients who underwent radical prostatectomy without immediate adjuvant radiation therapy (ART) but subsequently have evidence of recurrent disease are candidates for Salvage Radiati...

Real mobile robots should be able to build an abstract representation of the physical environment, in order to navigate and to work in such environment. We present a method for sensor-based exploration of unknown environments by mobile robots. This method proceeds by building a data structure called SRT (Sensor-based Random Tree). The SRT represents a roadmap of the explored area with an associ...

PURPOSE For prostate cancer that is thought to be locally recurrent after prostatectomy, the optimal timing, dose and techniques for salvage radiotherapy (SRT) have not been established. Here we perform a systematic review of published reports including regression meta-analysis and radiobiologic modelling to identify predictors of biochemical disease control and late toxicity. METHODS We perf...

This study was performed to investigate the feasibility of FDG- and L-[methyl-11C]methionine (Met)-PET for the follow up of lung cancer after stereotactic radiotherapy (SRT). Nine patients (pt) with solitary lung cancer underwent SRT. Met- and FDG-PET studies were performed one week before SRT and from one week to 8 months after SRT. Responses to SRT were complete in 2 pt and partial in 7 pt. M...

BACKGROUND For patients with recurrent prostate cancer after radical prostatectomy (RP), salvage radiotherapy (SRT) is a second chance of cure. However, depending on risk factors, 40-70% of the patients experience further progression. With a focus on the pre- and post-SRT serum level of the prostate-specific antigen (PSA), we assessed the determinants of the long-term outcome after SRT. PATIE...

This study was performed to investigate the feasibility of FDGand L-[methyl-11C]methionine (Met)-PET for the follow up of lung cancer after stereotactic radiotherapy (SRT). Nine patients (pt) with solitary lung cancer underwent SRT. Metand FDG-PET studies were performed one week before SRT and from one week to 8 months after SRT. Responses to SRT were complete in 2 pt and partial in 7 pt. Metan...