Reassessment of the ;gastric bactericidal barrier' to enteric bacteria in man included studies of the bactericidal activity of (1) the normal and achlorhydric stomach in vivo and (2) normal and achlorhydric gastric juice and other media in vitro. Within 30 minutes virtually all bacteria (Serratia marcescens) were eliminated in the normal stomach whereas no reduction occurred in the achlorhydric...

E SUCCESS of liver therapy in Addisonian pernicious anemia and the elucidation of the role of the stomach in blood formation are milestones of modern hematology. According to Castle’s hypothesis, normal gastric juice contains a special substance, intrinsic factor, produced by the gastric mucosa. This substance reacts with an extrinsic factor contained in the food. The production is an antianemi...

EDITORIAL SYNOPSIS The electrophoretic pattern of normal human gastric juice is described. The effect of autodigestion of gastric juice and of the peptic digestion of albumin is described. The fallacies involved in the study of gastric juice proteins where peptic digestion of the protein constituent has not been prevented are emphasized. In this study the gastric juice was neutralized within th...

Methods Amalaki Rasayana samples were tested for their antiulcer effect in Charles Foster’s strain albino rats and divided into 4 groups: Control and Ordinary Amalaki Rasayana (O.A.R.), Freeze Dried Amalaki Rasayana (F.D. A.R.), Freeze Dried Amalaki Churna (F.D.A.C.) (100mg/ kg body weight, 7 consecutive days). Gastric ulcer was induced by oral administration of aspirin (400 mg/kg) and with lig...

In view of the anomalous expression of blood group and related antigens in the gastric mucosae of patients with malignant and premalignant diseases of the stomach, and the potential clinical value of their measurement, a preliminary study has been performed on the blood group antigens A, B, H, Lea, Leb, and I(Ma) in glycoprotein rich extracts of the resting and tetragastrin stimulated gastric j...

In view of the anomalous expression of blood group and related antigens in the gastric mucosae of patients with malignant and premalignant diseases of the stomach, and the potential clinical value of their measurement, a preliminary study has been performed on the blood group antigens A, B, H, Lea, Leb, and I(Ma) in glycoprotein rich extracts of the resting and tetragastrin stimulated gastric j...

We compared two lactase preparations derived from Aspergillus orizae (AOL) and Penicillinase multicolor (PML) for stability in the stomach and overall enzymatic activity in 10 asymptomatic subjects with lactase deficiency. The subjects were given 10,000 FCC units of either AOL or PML 30 min prior to or simultaneously with 300 ml of milk. Gastric juice was withdrawn through a nasogastric tube im...

Few articles on concentration of pepsin in the gastric juice of patients with disease of the stomach and duodenum are to be found in recent literature, and the results reported by different observers are not always in accord. We shall consider here only the concentration of pepsin in the gastric juice of persons suffering with the syndrome of peptic ulcer. Wilcox (5), in 1908, reported that the...

Knowledge of digestion kinetics of solid foods in human stomach, as affected by food processing methods, is critical in establishing processing conditions at the manufacturing stage to achieve desirable release of nutrients in the gastrointestinal tract. The objective of this study was to investigate how roasting affected disintegration and solid release properties of almond in simulated gastri...

The isolation of group specific B substance from human stomach juice is described. The substance is carbohydrate-like in nature and is as potent as the carbohydrate-like substance group A isolated from commercial pepsin and peptone respectively.