Today’s CIO is faced with an increasingly complex business environment, making the strategic management of information systems (IS) a daunting task. Technological change, shifting customer needs and wants, and the trend toward globalization are just a few of the external factors that impact IS strategy during the formulation stage. Scenario planning is a technique that has been used in strategy...

In this paper, a recently developed model governing the cancer growth on a cell population level with combination of immune and chemotherapy is used to develop a reactive (feedback) mixed treatment strategy. The feedback design proposed here is based on nonlinear constrained model predictive control together with an adaptation scheme that enables the effects of unavoidable modeling uncertaintie...

The problem of concept formation and learning is examined from the viewpoint of granular computing. Correspondences are drawn between granules and concepts, between granulations and classifications, and between relations over granules and relations over concepts. Two learning strategies are investigated. A global attribute-oriented strategy searches for a good partition of a universe of objects...

Stochastic dominance constraints allow a decision-maker to manage risk in an optimization setting by requiring their decision to yield a random outcome which stochastically dominates a reference random outcome. We present new integer and linear programming formulations for optimization under first and second-order stochastic dominance constraints, respectively. These formulations are more compa...

Probabilistic design to address uncertainty and variability has been approached from many different angles, by different communities. While reliability methods focus on probability of constraint satisfaction or violation, robust design methods have focused primarily on the level of performance variation, the sensitivity of design objectives. “Six Sigma” quality concepts have arisen more recentl...

Tuberculosis (TB) is a bacterial disease responsible for millions of infections and preventable deaths each year. Its treatment is complicated by patients' noncompliance due to dosing frequency, lengthy treatment, and adverse side effects associated with current chemotherapy. However, no modifications to the half-a-century old standard chemotherapy have been made based on a nanoformulation stra...

Sustainable development is one of the most important issues that can be considered from different aspects and in different contexts including sustainable agriculture. This study aimed to investigate the main strategies related to sustainable development of rice production as an important agricultural product in Guilan Province using a SWOT analysis. To this end, different internal (strengths an...

car manufacturing industry is considered one of the major national industries, which due to its increasing product, particularly in recent years, has played a crucial role in the economy of the country, and still continues to do so. with the development of manufacturing capacity in the car industry, a relative competition is being witnessed among the manufacturers, which calls for the considera...