churg-strauss syndrome (css) is a granulomatous small vessel vasculitis . it is characterized by asthma, allergic granulomatosis and vasculitis . this syndrome is rare in children. a 5 years old boy was admitted with cough, fever and dyspnea for 2 weeks. on the basis of  laboratory data (peripheral eosinophilia), associated with skin biopsy, and history of css in his sister, this disease was ev...

Churg-Strauss syndrome, a small and medium vessel vasculitis, was first described by Churg and Strauss in 1951. It is characterised by the presence of asthma, prominent tissue and blood eosinophilia, systemic vasculitis, and pulmonary and systemic necrotising allergic granulomas. Involvement of the skin, heart and gastrointestinal tract is well documented, but ocular presentation is unusual. We...

a 56-year-old woman came in with abdominal pain, nausea, vomiting, fever, 15 kg weight loss and accelerated asthma for which she had used zafirlukast and a high dose of prednisolone. during taper down of her prednisolone, her condition deteriorated. she developed generalized wheezing, diffuse abdominal pain, and left foot drop. lab examination revealed eosinophilia, elevated red cell sedimentat...

A patient with Churg-Strauss vasculitis presenting with mononeuritis multiplex, who developed obstructive jaundice, is described. On investigation the jaundice proved to be due to ascaris infestation. As the immune abnormalities associated with ascaris infection are also typical of those seen in the Churg-Strauss syndrome it is speculated that the vasculitis occurred because of a failure to reg...

Churg-Strauss syndrome is an eosinophil-associated, small vessel granulomatous vasculitis, characterized by late onset asthma, upper airways disease, eosinophilia, and clinical manifestations of systemic vasculitis. Several cases of Churg-Strauss syndrome have been recognized in patients treated with cysteinyl leukotriene-receptor antagonists and weaned off systemic corticosteroids. These cases...

Churg-Strauss syndrome is a small and medium vessel vasculitis and is also known as allergic granulomatous angiitis. Gastrointestinal involvement is common in patients with Churg-Strauss syndrome (20-50%). The most common symptoms are abdominal pain, diarrhoea and occasionally gastrointestinal bleeding and perforation. We present a case of Churg-Strauss syndrome with small bowel lesions documen...

BACKGROUND Churg-Strauss is a rare, idiopathic, hypereosinophilic disease characterized by blood, tissue, and systemic vasculitis in patients with a history of asthma or allergic rhinitis. Gastrointestinal manifestations of Churg Strauss appear in a 31-45% of the patients according to some series of studies, abdominal pain being the most frequent symptom followed by diarrhea and bleeding. CLI...

In 1951 the pathologists Churg and Strauss identified 13 patients who presented with a clinical syndrome characterised by asthma, hypereosinophilia, and evidence of vasculitis aVecting a number of organs. The three main histological features found on pathological examination of these cases were extravascular granulomas, tissue eosinophilia, and necrotising vasculitis (fig 1). Most of these pati...

churg strauss syndrome (css) is a form of primary vasculitis that is characterized by severe eosinophilia and often granulomatous inflammation as well as history of asthma or allergy. previously, the association between cysteinyl leukotrien receptor antagonists (ltras), corticosteroid withdrawal or a sudden change in its used method and css had been established. we report three cases that have ...

CHURG-STRAUSS SYNDROME Churg-Strauss syndrome is a rare small vessel vasculitis manifested by fever, asthma, and hypereosinophilia. This disease is also referred to as allergic angiitis and granulomatosis, • A patient’s combined genetic predisposition and regulatory mechanisms control expression of the immune response to antigens. • Negative test results for antineutrophil cytoplasmic antibodie...