Diabetes merupakan penyakit kronis yang terjadi di saat insulin diproduksi oleh tubuh tidak bisa digunakan secara efektif maupun organ pankreas mengalami masalah dimana dapat sebagaimana mestinya. Mellitus dibagi menjadi dua jenis yaitu IDDM (DM tipe I) dan NIDDM 2. Kebaruan penelitian ini menguji efektivitas nonherbal kemangi sebagai antihiperglikemia pada tikus diabetes terindukasi streptozot...

background: quercetin is a strong antioxidant and long-term treatment of stz-diabetic animals and it has been shown to reduce oxidative stress.   objective: antioxidants have essential effect on spermatogenesis and sperm parameters. enhanced oxidative stress and changes in antioxidant capacity are considered to play an important role in the pathogenesis of chronic diabetes mellitus.   methods: ...

background: ginger rhizome (zingiber officinale r., family: zingiberaceae) is used medicinally and as a culinary spice. the medicinal use of ginger dates back to ancient china and india. objective: ginger and its constituents are stated to have antiemetic, antithrombotic, antihepatotoxic, anti-inflammatory, stimulant, cholagogue and antioxidant.enhanced oxidative stress and changes in antioxida...

background: diabetes mellitus in some clinical cases is accompanied with hyperalgesia. in this study, we evaluated the possible beneficial effect of chronic pelargonidin (pg) treatment on hyperalgesia in streptozotocin (stz)-diabetic neuropathic rat. methods: male wistar rats (n = 56) were divided into seven groups, i.e. control, diabetic, pg-treated control, pg (single- and multiple-dose)-trea...

background: diabetes is the most common endocrine disease. it has adverse effects on male reproductive function. royal jelly (rj) has antioxidant and anti-diabetic effects and show protective effects against diabetes. objective: this study was conducted to evaluate the effect of rj on histopathological alterations of the testicular tissue in streptozotocin (stz)-induced diabetic rats. materials...

objective: as the aqueous extract of capparis spinosa (cs) possess antidiabetic effect, he present study aims to reveal the possible  mechanism of action of cs in diabetic mice.materials and methods: both single and repeated oral administrations of aqueous extract of cs were performed in multi-low dose streptozotocin-induced (mlds) diabetic mice. euglycemic hyperinsulinemic clamp was used in as...

today diabetes is one of the most common diseases in the world that affects half of the world population. today, the use of medicinal herbs especially green tea and cinnamon has been taken into consideration for relieving the symptoms of diabetes, but there were some different ideas about their effectiveness. so, this study was conducted to evaluate the effect of cinnamon and green tea extract,...

background: danae racemosa is a strong antioxidant and antioxidants have significant effects on spermatogenesis, sperm biology and oxidative stress, and changes in antioxidant capacity are considered to be involved in the pathogenesis of chronic diabetes mellitus. objective: because stz causes testicular dysfunction and degeneration under situations of experimentally induced diabetes in animal ...

objective: the present study was hypothesized to investigate the beneficial effects of fresh, aged, and cooked garlic extracts on blood glucose and memory of diabetic rats induced by streptozocine (stz). material and methods: diabetes was induced by an intraperitoneal injection of stz (60 mg/kg body weight). an oral dose of 1000 mg/kg of each garlic extract was given daily for 4 weeks after dia...

Diabetes may lead to the development of osteoporosis. Coffee drinking, apart from its health benefits, is taken into consideration as an osteoporosis risk factor. Data from human and animal studies on coffee and caffeine bone effects are inconsistent. The aim of the study was to investigate effects of caffeine at a moderate dose on the skeletal system of rats in two models of experimental diabe...