background of the study: colorectal cancer (crc) which is the third most diagnosed cancer throughout the world is steadily rising in the asian countries with the incidence rates mimicking the western counterparts. the pre-neoplastic nature of the transitional mucosa (tm) adjoining crc lacks conclusive evidence so far. pertaining to this, the study of the mucus layer, the functional component of...

Introduction: Autism is a heterogeneous neurodevelopmental disorder associated with social, cognitive and behavioral impairments. These impairments are often reported along with alteration of the brain structure such as abnormal changes in the grey matter (GM) density. However, it is not yet clear whether these changes could be used to differentiate various subtypes of autism spectrum disorder ...

the effect of mechanical activation on structural changes and kinetics of carbothermic reduction of hematite with graphite was studied in this research. hematite powder mixture with graphite (with stoichiometry ratio c/o=1) was milled for the time periods of zero to 50 hours, and the structural changes were studied using x ray diffraction (xrd). the effect of mechanical activation on the kineti...

Troponin senses Ca2+ to regulate contraction in striated muscle. Structures of skeletal muscle troponin composed of TnC (the sensor), TnI (the regulator), and TnT (the link to the muscle thin filament) have been determined. The structure of troponin in the Ca(2+)-activated state features a nearly twofold symmetrical assembly of TnI and TnT subunits penetrated asymmetrically by the dumbbell-shap...

Software engineers strive to understand software’s evolution and make software better and more reliable. In the last decade, software’s life cycle became an interesting research area. However, software evolution could be analyzed from different aspects. In the study, we focused on analyzing structural software changes between software’s versions. We used the WatiN project and observed its struc...

We investigated how volumes of cerebrospinal fluid (CSF), grey matter (GM) and white matter (WM) varied with age, sex, small vessel disease and cardiovascular risk factors in the Rotterdam Scan Study. Participants (n=490; 60-90 years) were non-demented and 51.0% had hypertension, 4.9% had diabetes mellitus, 17.8% were current smoker and 54.0% were former smoker. We segmented brain MR-images int...

Back pain is an extremely common symptom and is experienced by over half the adult population (Lawrence, 1969). In some cases, well-defined causes such as a prolapsed intervertebral disc or ankylosing spondylitis can be recognized, but in the majority no precise cause can be identified. In this paper, a series of studies of the structure of the intervertebral disc is reported, and possible mech...