background: sulfur mustard (sm) has been considered as a carcinogen in the laboratory studies. however, its carcinogenic effects on human beings were not well discussed. the main purpose of our study is to assess carcinogenesis of sm following acute and/or chronic exposures in human beings. methods: the valid scientific english and persian databases including pubmed, web of science, scopus, ira...

purpose : to review current knowledge about ocular effects of sulfur mustard (sm) and the associated histopathologic findings and clinical manifestations methods : literature review of medical articles (human and animal studies) was accomplished using pubmed, scopus and isi databases. a total of 274 relevant articles in english were retrieved and reviewed thoroughly. results : eyes are the most...

Sulfur mustard (bis[2-chloroethyl]sulfide; C4H8Cl2S; CASRN: 505-60-2) or as it is commonly called, ‘mustard gas’, is one of a class of vesicant chemical warfare agents with the ability to form vesicles or blisters on exposed skin. Sulfur mustard is a viscous liquid at ambient temperature, but becomes a solid at 58 °F (14 °C). It is heavier than water as a liquid and heavier than air as a vapor....

purpose: to determine any possible correlation between delayed ocular complications with late-onset complications of mustard gas poisoning in other systems including skin, respiratory tract, and immunohematologic system. methods: the study was conducted on 40 chemical war victims in khorasan province, iran. ophthalmologic and dermatologic examinations and spirometry were performed for all patie...

the aim of this study was to compare the total protein levels in serum of veteran exposure to sulfur mustard (sm) which was used in the iran-iraq war. in this study, 35 patients exposed to mustard gas (case group) and 35 healthy subjects (control group) were evaluated. the total protein concentration was measured by bradford method. the average amount of protein in serum exposure to sulfur must...

Background: Sulfur mustard gas is a chemical agent that has been used in many wars, especially in Iran-Iraq war. This chemical agent affects many organs including lungs, eyes and skin, causing numerous acute and chronic lesions including erythema and hyperpigmentation, respectively. This study was conducted to evaluate erythema and melanin in subjects with a history of exposure to sulfur ...

Sulfur mustard or mustard gas has been widely used as a chemical weapon in the first world war and Iraq-Iran war. It causes acute and chronic complications in lungs, eyes and skin. In skin, mustard is toxic, mutagenic, and carcinogenic via alkylation of cellular proteins in enzymes, cell membranes, cytoplasm and particularly cell nucleus as well as in DNA components of the epidermis, dermis and...

Following an accidental human exposure to a vesicating agent, plasma samples were analyzed for specific biomarkers of sulfur mustard. One individual suffered chemical burns over 6.5% of the body surface area and required hospitalization; the second individual developed a single, small blister. Plasma specimens from both individuals were examined using two different assays. The first assay targe...

PURPOSE In patients with short-term exposure to the sulfur mustard gas, the delayed cellular effects on lungs have not been well understood yet. The lung pathology shows a dominant feature consistent with obliterative bronchiolitis, in which fibroblasts play a central role. This study aims to characterize alterations to lung fibroblasts, at the cellular level, in patients with delayed respirato...

Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma. Persistent antigenic stimulation has been claimed to play a role in the development of this malignancy. We aimed to show the role of sulfur mustard in the pathogenesis of MF. A 45-year-old man with MF is introduced herein. He was a victim of chemical exposure in 1987 during the Iran–Iraq war. He developed skin lesions ...