نتایج جستجو برای: superovulation

تعداد نتایج: 667  

2017
Myungook Lee Jong Il Ahn Ah Ran Lee Dong Woo Ko Woo Sub Yang Gene Lee Ji Yeon Ahn Jeong Mook Lim

Regular monitoring on experimental animal management found the fluctuation of ART outcome, which showed a necessity to explore whether superovulation treatment is responsible for such unexpected outcome. This study was subsequently conducted to examine whether superovulation treatment can preserve ultrastructural integrity and developmental competence of oocytes following oocyte activation and ...

2016
Juan-Ke Xie Qian Wang Ting-Ting Zhang Shen Yin Cui-Lian Zhang Zhao-Jia Ge

Controlled ovarian stimulation by exogenous gonadotrophins is a key procedure during the in vitro fertilization cycle to obtain a sufficient number of oocytes in humans. Previous studies demonstrated that repeated superovulation had deleterious effects on the ovaries. However, whether repeated superovulation adversely affects the mitochondrial functions of cumulus cells remains unclear. In this...

Journal: :Human molecular genetics 2010
Brenna A Market-Velker Liyue Zhang Lauren S Magri Anne C Bonvissuto Mellissa R W Mann

Superovulation or ovarian stimulation is currently an indispensable assisted reproductive technology (ART) for human subfertility/infertility treatment. Recently, increased frequencies of imprinting disorders have been correlated with ARTs. Significantly, for Angelman and Beckwith-Wiedemann Syndromes, patients have been identified where ovarian stimulation was the only procedure used by the cou...

2006
Zhongle Chang Xinzhong Fan Mingjiu Luo Zhanyuan Wu Jinghe Tan

Despite many studies, results of superovulation protocols are not consistent in farm animals. In this study, 151 Boer goats were superovulated to examine the factors affecting superovulation and embryo transfer (MOET). An optimal regime for superovulation treatment was identified as a 4-day treatment with decreasing dosages of 6-7 mg Chinese FSH or 240 mg Canadian FSH. The 4-day treatment with ...

Journal: :Reproduction, fertility, and development 2015
Jing Shu Li-Li Xing Guo-Lian Ding Xin-Mei Liu Qing-Feng Yan He-Feng Huang

A mouse model was used to compare the number and function of mitochondria in oocytes and embryos obtained by superovulation and in a natural cycle (control group). The superovulation group had a higher number of total oocytes, MII oocytes, embryos with two pronuclei, 2-cell embryos and blastocysts than the control group (P<0.05 for all). The superovulation group had high proportion of MII oocyt...

Journal: :Human molecular genetics 2008
Amanda L Fortier Flavia L Lopes Nicole Darricarrère Josée Martel Jacquetta M Trasler

Imprinted genes play important roles in embryonic growth and development as well as in placental function. Many imprinted genes acquire their epigenetic marks during oocyte growth, and this period may be susceptible to epigenetic disruption following hormonal stimulation. Superovulation has been shown to affect growth and development of the embryo, but an effect on imprinted genes has not been ...

2015
Toru Takeo Naomi Nakagata Cheryl S. Rosenfeld

Superovulation is a reproductive technique generally used to produce genetically engineered mice. Superovulation in mice involves the administration of equine chorionic gonadotropin (eCG) to promote follicle growth and then that of human chorionic gonadotropin (hCG) to induce ovulation. Previously, some published studies reported that inhibin antiserum (IAS) increased the number of ovulated ooc...

2017
Marja Mikkola

........................................................................................................... 6 ORIGINAL ARTICLES ......................................................................................... 8 ABBREVIATIONS ................................................................................................. 9 INTRODUCTION .....................................................

Journal: :Reproduction, nutrition, developpement 1987
S Torrès C Sevellec

Repeated superovulation using three treatments of pFSH at intervals of 45 to 55 days during the same breeding season was carried out in 18 Préalpes ewes. The embryos were recovered by surgery after the first two treatments and by slaughter after the last one at Day 6. Three lots of control ewes (n = 5 or 6) receiving the same superovulation treatment were slaughtered respectively at the same ti...

2013
Jung Kyu Choi Xiaoming He

BACKGROUND The outbred (as with humans) deer mice have been a useful animal model of research on human behavior and biology including that of the reproductive system. One of the major challenges in using this species is that the yield of oocyte isolation via superovulation is dismal according to the literature to date less than ∼5 oocytes per animal can be obtained so far. OBJECTIVE The goal ...

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