Some methods for examining the additivity of sweeteners, and their synergy in mixtures depend upon setting component concentrations on the basis of sweetness equivalence, usually to a sucrose reference. These methods may under- or over-predict the sweetness of a mixture, leading to spurious claims of synergy or mixture suppression. This paper points out one problem with one such popular method,...

Where phages are used to treat bacterial contaminations and infections, multiple phages are typically applied at once as a cocktail. When two or more phages in the cocktail attack the same bacterium, the combination may produce better killing than any single phage (synergy) or the combination may be worse than the best single phage (interference). Synergy is of obvious utility, especially if it...

Standing up is fundamental to daily activities of the elderly. It is necessary both to enhance muscle strength and to strengthen muscle coordination for improvement of their motor function. In this paper, we extract important data related to muscle coordination, called synergy, to perform standing motion by young and elderly participants. The contribution of muscle synergy to body kinematics is...

The performance of a team at a task depends critically on the composition of its members. There is a notion of synergy in human teams that represents how well teams work together, and we are interested in modeling synergy in multiagent teams. We focus on the problem of team formation, i.e., selecting a subset of a group of agents in order to perform a task, where each agent has its own capabili...

Food contains various taste substances. Among them, umami substances play an important role with regard to the perception of the taste of food, but, few studies have examined the taste characteristics of representative umami substances other than monosodium L-glutamate (MSG). By conducting mouse behavioral studies (the 48-h 2-bottle preference test and the conditioned taste aversion test) and a...

An interesting exploration in the field of phytotherapy, is in the area of ‘synergy’ which was advanced in a landmark paper by Williamson (2001) and further highlighted by Ulrich-Merzenich et al. (2007). The concept relates to the growing evidence that plant constituents may provide a ‘super additive’ biological effect when combined, as opposed to being just the sum of their individual parts (e...

Fosmidomycin (FR-31564), a phosphonic acid derivative, was combined with cefazolin, cephalexin, ampicillin, carbenicillin, ticarcillin, gentamicin, and trimethoprim. Synergy between fosmidomycin and penicillins or cephalosporins was found for 37 to 52% of the Enterobacteriaceae tested. Synergy with trimethoprim was found against 55% of bacteria isolated, but only 17% of the strains showed syner...

Restructuring  is relevant for companies that have free capital and need to expand for development purposes, as well as for companies that have relatively large problems with financial results and the relevant indicators indicate the necessary changes. Motives of the restructuring may be different, the authors put forward the following reasons: operation operational synergy, financial synergy, ...