BACKGROUND AND AIM Chronic hepatic damage leads to liver fibrosis, which is characterized by the accumulation of collagen-rich extracellular matrix. However, the mechanism by which E3 ubiquitin ligase is involved in collagen synthesis in liver fibrosis is incompletely understood. This study aimed to explore the involvement of the E3 ubiquitin ligase synoviolin (Syno) in liver fibrosis. METHOD...

A synapse is the junction across which a nerve impulse passes from an axon terminal to a neuron, muscle cell or gland cell. The functions and building molecules of the synapse are essential to almost all neurobiological processes. To describe synaptic structures and functions, we have developed Synapse Ontology (SynO), a hierarchical representation that includes 177 terms with hundreds of synon...

A re-description is given of the problematic genus and species Scatocoenosia cordyluraeformis Schnabl, 1915. Illustrations of the male and female terminalia, and images of the female holotype and the male of this species, are given. The syno-nymy of Scatocoenosia Schnabl, 1915 with Spilogona Schnabl, 1911 is confirmed, and notes are given on the relationships of S. cordyluraeformis with other S...

this project was conducted to study the taxonomy of tribe vicieae based on morphological characters. the specimens were collected from different parts of khorassan, and after identification they were preserved at ferdowsi university of mashhad herbarium (fumh). diagnostic keys and a complete list of distribution regions for all species of this tribe in khorassan were presented. cicer kermanense...

'LFulbright Research Scholar, Department of Medicine, Oslo University, 1953-1954. 2 Present Address: Hematology Section, Veterans Administration Hospital, Long Beach, California. There is no standard nomenclature for the newer clotting factors. The following terms are used in this paper. Blood thromboplastin is used in its classic meaning of an activity which arises during clotting and which is...

This paper describes a syntax oriented spoken japanese understanding system named "SPOJUS-SYNO". At first, this system makes word HMMs automatical!y by concatenating syl!able-based (trained) HMMs. Then a word lattice is hypothesized by using a word spotting algorithm and word-based HMMs. Final!y, the timesynchronous left-to-right parsing algorithm is executed to find the best word sequence from...

Many different opinions are observed if one compares the denomination of the species of relapsing fever spirochaetes by different authors. Brumpt (1) describes 14 different species in his extended Parasitology and Stitts (2) 18, but he admits the possibility of synonyms among them. Napier (3) mentions that the application of names of the countries in which the spirochaetes occur implicates the ...

This review focuses on the contributions made by interactions between dendritic cells (DCs) and T cells, and by local production of cytokines and chemokines to the pathogenesis of rheumatoid arthritis (RA) synovitis. DCs are efficient professional antigen-presenting cells, which are critical for the development of innate and adaptative immune responses through interactions with T cells. Cytokin...

341 In the first days after a magnitude 8.7 earthquake leveled buildings on the Sumatran islands of Nias and Simeulue on 28 March, experts wondered why it failed to generate a significant tsunami. After all, the monster quake that struck just to the north in Decem-ber spawned a tsunami that killed more than a quarter-million people. Now that they've had a chance to locate the fault rupture more...

Cruz Biotechnology), anti-FLAG (M2; Sigma Chemical Co., St. Louis, MO), anti-β-actin (AC-15; Sigma), and anti-α-tubulin (B-5-1-2; Sigma Chemical Co.) were used. Anti-Synoviolin monoclonal antibody (10Da) was reported previously (Amano et al., 2003). Cycloheximide (Sigma Chemical Co., 100μg/mL) was used for the chase experiment of p53. Camptothecine (Sigma, 0.5 mM), and actinomycin D (Sigma Chem...