A modified fixed-ratio isobologram method for studying the in vitro interactions between antiplasmodial drugs is described. This method was used to examine the interactions between atovaquone, proguanil, and dihydroartemisinin. The interaction between atovaquone and proguanil was synergistic against atovaquone-sensitive strains K1 and T996; however, there was a loss of synergy against atovaquon...

penfluridol, a neuroleptic drug, considerably reversed halofantrine resistance in t9.96hf halofantrine resistant strain of plasmodium falicparum (originally chloroquine sensitive parasites), but not in k1hf halofantrine resistant strain (originally chloroquine resistant parasites)

The monitoring and regulation of one's own physiological reactions and cardioregulatory abnormalities are central to the aetiology and maintenance of social anxiety disorder (SAD). We therefore explored the neural correspondences of these heart rate alterations. 21 patients with SAD and 21 matched healthy controls (HCs) underwent 3T-fMRI scanning. Simultaneously, high-frequency heart rate varia...

in this study, absorption of high frequency radio waves in the ionospheric plasma have beeninvestigated. the wave equation was obtained in terms of ionospheric parameters. the numerical values ofthe absorption have been calculated for 4 mhz, 4.5 mhz and 5 mhz waves. the necessary parameters forcalculation have been obtained using an international reference ionosphere (iri) model. the altitudina...

Hf-phosphinoamide cation complexes behave as metal-based frustrated Lewis pairs and bind one or two equivalent of CO2 and in as well can activate CO2 in a bimetallic fashion to give a pseudo-tetrahedral P2CO2 fragment linking two Hf centres.

An array of SeaSonde HF radars has been deployed along the Oregon coast by P. M. Kosro of the College of Oceanic and Atmospheric Sciences, OSU. Data from a two-site HF array, which provides measurements of surface currents over a region about 50 km square, have been collected since November 1997. This project is aimed initially at developing and applying, in cooperation with Kosro, methods for ...

The thermal unimolecular dissociation of CH3F was studied in shock waves by monitoring the UV absorption of a dissociation product identified as CH2F. It is concluded that, under conditions applied, the formation of this species corresponds to a minor, spin-allowed, dissociation channel of about 3% yield. Near to the low-pressure limit of the reaction, on the other hand, the energetically more ...

In the Netherlands there is a nationwide premium rate telephone number that can be dialed to obtain information about various forms of public transport. In t996 this number was called more than twelve million times. Human operators managed to handle only about nine million of these calls. In order to answer more of these calls, a spoken dialog system was developed to automate part of this servi...

Objective(s): Existing studies have demonstrated that intravenous and intramyocardial-administrated mesenchymal stem cells (MSCs) lead to tissue repair after cardiac disorders. We compared the efficiency of both administration methods.Materials and Methods: A rat model of isoproterenol-induced heart failure (ISO-HF) was established to co...