objective: administration of amoxicillin and metronidazole along with scaling and root planning (srp) is an effective adjunctive therapy for chronic periodontitis. studies have shown that administration of azithromycin is also effective for treatment of chronic periodontitis. this study aimed to compare the effect of short-term and long-term azithromycin regimen with amoxicillin and metronidazo...

23 The adverse effects of azithromycin on the treatment of patients with chronic lung 24 diseases (CLD) were evaluated in the present study. 25 MEDLINE, and other databases were searched for relevant articles till August 2013. 26 Randomized controlled trials enrolled patients with chronic lung diseases who 27 received long-term azithromycin treatment were selected and data on microbiological 28...

23 The adverse effects of azithromycin on the treatment of patients with chronic lung 24 diseases (CLD) were evaluated in the present study. 25 MEDLINE, and other databases were searched for relevant articles till August 2013. 26 Randomized controlled trials enrolled patients with chronic lung diseases who 27 received long-term azithromycin treatment were selected and data on microbiological 28...

BACKGROUND The aim of this study was to determine whether long-term intermittent azithromycin therapy reduces the frequency of exacerbation in severe chronic obstructive pulmonary disease (COPD). METHODS We retrospectively investigated the clinical benefits of long-term azithromycin (500 mg orally three times per week) over 12 months in patients with severe COPD and a minimum of four acute ex...

Long-term immunosuppressive therapy with severe adverse effects is indispensable to maintain disease remission in frequently relapsing nephrotic syndrome (NS) in children. Hence, development of new therapy with less toxicity for relapses of NS is required. We demonstrated a case of a 2-year-old boy with frequently relapsing NS, whose frequent relapses were successfully treated with azithromycin...

Respir Rev 2005;6:227–35. 41. Equi A, Balfour-Lynn IM, Bush A, et al. Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial. Lancet 2002;360:978–84. 42. Wolter J, Seeney S, Bell S, et al. Effect of long term treatment with azithromycin on disease parameters in cystic fibrosis: a randomised trial. Thorax 2002;57:212–16. 43. Saiman L, Marshall B...

Authors: Uzun S, Djamin RS, Kluytmans JAJW, et al. Lancet Respir Med 2014; 2: 361–368 Summary: This study represents a significant development in the use of long-term azithromycin maintenance treatment in a subgroup of patients with chronic obstructive pulmonary disease (COPD). Patients with .3 exacerbations in the preceding year were randomised to receive thrice-weekly placebo or azithromycin ...

Azithromycin is a potent macrolide antibiotic with poorly understood antiinflammatory properties. Long-term use of azithromycin in patients with chronic inflammatory lung diseases, such as cystic fibrosis (CF), results in improved outcomes. Paradoxically, a recent study reported that azithromycin use in patients with CF is associated with increased infection with nontuberculous mycobacteria (NT...

We thank Dr Vos and colleagues for providing important additional studies that support the use of long-term azithromycin therapy to treat and, possibly, prevent posttransplant bronchiolitis obliterans syndrome (BOS). These studies should have been included in our review of chronic macrolide therapy in infl ammatory airways disease 1 but were not available at the time of submission. Their recent...