sirolimus is a potent immunosuppressive agent administered as prophylactic agent to prevent rejection after organ transplantation. sirolimus must be used within a narrow therapeutic window. due to inter- and intra-variability, sirolimus blood concentrations may be affected, therefore, there is no possibility of predicting the sirolimus blood concentrations based on the dose patients received. t...

the purpose of this paper was to review the commercially available periodontal dressings, their physical and chemical properties, biocompatibility and therapeutic effects. electronic search of scientific papers from 1956 to 2012 was carried out using pubmed, scopus and wiley interscience search engines using the searched terms periodontal dressing, periodontal pack. numerous in vitro and in viv...

receptors and proteins are overexpressed in many human cancer cell membranes rather than normal tissues and are considered as the main molecular targets. specific tumor- targeting molecules which have high affinity for these receptors can be valuable tools as carrier molecules for targeted cancer therapy and imaging. pharmacokinetics and bioavailability of diagnostic and therapeutic agents are ...

This article has no abstract