نتایج جستجو برای: toll like receptor 4

تعداد نتایج: 2315698  

Journal: :iranian journal of allergy, asthma and immunology 0
simin almasi firouzgar hospital, iran university of medical sciences (iums), tehran, iran saeed aslani rheumatology research center, tehran university of medical sceinces, tehran, iran hadi poormoghim firouzgar hospital, iran university of medical sciences (iums), tehran, iran ahmad reza jamshidi rheumatology research center, tehran university of medical sciences, tehran, iran shiva poursani rheumatology research center, tehran university of medical sceinces, tehran, iran mehdi mahmoudi rheumatology research center, tehran university of medical sceinces, tehran, iran

no abstract

Journal: :journal of cellular and molecular anesthesia 0
bahador bagheri cancer research center and department of pharmacology, semnan university of medical sciences, semnan, iran seyed sajad razavi ali gohari sara salarian anesthesiology research center, shahid beheshti university of medical sciences, tehran, iran ali dabbagh

toll like receptors (tlrs) recognize pathogens and generate an immediate defense response by inducing the production of pro-inflammatory cytokines, which rapidly destroy or limit the pathogens. in their bridging role, tlr downstream signals link innate and adaptive immunity, particularly by mediating dc maturation and activation of pathogen specific t lymphocytes. these pathways lead to the act...

Journal: :iranian biomedical journal 0
بهادر باقری bahador bagheri بهرام سهرابی bahram sohrabi علی اکبر موثق پور ali akbar movassaghpour سیمین مشایخی simin mashayekhi آفاق گرجانی afagh garjani مهریار شکری mehriar shokri مسعود پزشکیان

bacground: evidence from several lines of investigations suggests that toll-like receptor 4 (tlr4) is involved in atherosclerosis as a bridge between innate and acquired immunity. percutaneous coronary intervention (pci) can trigger inflammation through activation of human tlr4 (htlr4) on monocytes. hydrocortisone as an anti-inflammatory and immuno-suppressant agent has multiple mechanisms of a...

Journal: :gene, cell and tissue 0
seyed mohammad hashemi-shahri infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran mohsen taheri genetics of non-communicable disease research center, zahedan university of medical sciences, zahedan, ir iran; department of genetics, school of medicine, zahedan university of medical sciences, zahedan, ir iran; department of genetics, school of medicine, zahedan university of medical sciences, zahedan, ir iran. tel: +98-5413425793, fax: +98-5413425796 ali gadari infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran mohammad naderi infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran gholamreza bahari department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran mohammad hashemi department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran

conclusions tlr8 rs3764880 and tlr9 rs148805533 polymorphisms may not be risk factors for susceptibility to tuberculosis in a sample of iranian population. larger studies are required to validate our findings. results the allelic and genotypic frequencies of the tlr8 rs3764880 did not differ significantly between ptb and the controls. no significant difference was found between the groups regar...

Journal: :hepatitis monthly 0
mahsa motavaf department of microbiology, islamic azad university of varamin-pishva, varamin, ir iran; department of molecular hepatology, middle east liver disease center (meld), tehran, ir iran fatemeh noorbakhsh department of microbiology, islamic azad university of varamin-pishva, varamin, ir iran seyed moayed alavian department of molecular hepatology, middle east liver disease center (meld), tehran, ir iran zohreh sharifi department of microbiology, islamic azad university of varamin-pishva, varamin, ir iran; blood transfusion research center, high institute for research and education in transfusion medicine, tehran, ir iran; blood transfusion research center, high institute for research and education in transfusion medicine, tehran, ir iran. tel: +98-2182052233, fax: +98-88601555

conclusions this study suggests that decrease in levels of tlr3 and tlr7 expression is a mechanism that may enable hcv to evade the host innate immune response. results in both groups, we had 13 males and 12 females with a mean age of 48.7 ± 16. tlr3 (6.23 ± 0.91 vs. 3.89 ± 0.85, p < 0.001) and tlr7 (1.48 ± 0.82 vs-1.33 ± 1.18, p < 0.001) expressions were significantly lower in patients with ch...

Journal: :iranian journal of immunology 0
maryam rameshrad student research committee nasrin maleki-dizaji department of pharmacology, faculty of pharmacy, tabriz university of medical sciences, tabriz haleh vaez department of pharmacology, faculty of pharmacy, tabriz university of medical sciences, tabriz hamid soraya department of pharmacology, faculty of pharmacy, urmia university of medical sciences, urmia ailar nakhlband research center for pharmaceutical nanotechnology alireza garjani cardiovascular research centre, tabriz university of medical sciences, tabriz, iran

background: myocardial dysfunction is one of the major complications in patients with sepsis where there is a relationship between the blood level of cytokines and the onset of myocardial depression. in many cases of sepsis, the presence of lipopolysaccharide (lps) has been established. lps binding protein (lbp) bound endotoxin is recognized by cd14/toll-like receptor-4 (tlr4) complexes in inna...

Journal: :iranian journal of diabetes and obesity 0
ali dehghani firoozabadi yazd cardiovascular research center, shahid sadooghi university of medical sciences, yazd, iran.department of biology, faculty of science, ferdowsi university of mashhad, mashhad-iran. samaneh shojaeii immunology section, department pathobiology, faculty of veterinary medicine, ferdowsi university of mashhad, mashhad-iran. biotechnology section, department of pathology, faculty of veterinary medicine, ferdowsi university of maashhad, mashhad-iran. alireza haghparast immunology section, department pathobiology, faculty of veterinary medicine, ferdowsi university of mashhad, mashhad-iran. biotechnology section, department of pathology, faculty of veterinary medicine, ferdowsi university of maashhad, mashhad-iran. hamidreza dehghani firoozabadi department of biology, faculty of science, isfahan university, isfahan, iran.

abstract objective: the previous studies indicated that the tlrs especially toll-like receptor 4) tlr4 (are involved in the process of diabetes. the aim of the present research was to investigate the time course expression pattern of tlr4-a main component of innate immune system- in mrna levels in the heart tissue of diabetic male wistar rats. materials and methods: in this research, adult wist...

ژورنال: :gene, cell and tissue 0
saeedeh salimi cellular and molecular research center, zahedan university of medical sciences, zahedan, ir iran; department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran; department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran. tel: +98-5413425728

Journal: :hepatitis monthly 0
mahdi dehghan-manshadi immunology department, faculty of medicine, shahid sadoughi university of medical sciences, yazd, ir iran hossein hadinedoushan immunology department, faculty of medicine, shahid sadoughi university of medical sciences, yazd, ir iran; immunology department, reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, ir iran; immunology department, reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, ir iran. tel: +98-3536285406; +98-9133576620, fax: +98-3536238561 mohammad kazem amirbaigy gastrology department, faculty of medicine, shahid sadoughi hospital, shahid sadoughi university of medical sciences, yazd, ir iran fateme zare immunology department, faculty of medicine, shahid sadoughi university of medical sciences, yazd, ir iran gilda eslami parasitology and mycology department, shahid sadoughi university of medical sciences, yazd, ir iran seyyed ali mirghanizade-bafghi immunology department, faculty of medicine, shahid sadoughi university of medical sciences, yazd, ir iran

conclusions our findings showed that hcv infection could lead to increased expression level of tlr7 mrna in peripheral blood cells of hcv infected samples. the viral load and genotypes of hcv did not affect the mrna expression levels of tlr2 and tlr7. background hepatitis c virus (hcv) is an important human pathogen affecting an estimated 120 – 170 million individuals in the world. toll-like re...

Journal: :iranian journal of immunology 0
alireza haghparast laboratory of immunoregulation, department of pathobiology, faculty of veterinary medicine maryam heidari kharaji laboratory of immunoregulation, department of pathobiology, faculty of veterinary medicine amir mohammad malvandi laboratory of immunoregulation, department of pathobiology, faculty of veterinary medicine

background: pattern recognition receptors (prrs) are the main sensors of pathogen and danger signals in innate immunity of which toll like receptors (tlrs) are the most studied ones. the contribution of prrs in cerebral inflammation induced by microbial infection, tissue damage and cancer has not extensively been addressed so far. glioma is the most common tumor of the central nervous system an...

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