background: when we perform surgery in utero, lungs have an appropriate time to decrease magnitude of hypoplasia, with surgery in uterus. methods: six time-dated single-fetus ewes were selected to induce diaphragmatic hernia. fetal lambs were divided proportionally into 2 groups, namely group 1, diaphragmatic hernia and tracheal ligation (tl group), and group 2, diaphragmatic hernia only (nl gr...

BACKGROUND: When we perform surgery in utero, lungs have an appropriate time to decrease magnitude of hypoplasia, with surgery in uterus. METHODS: Six time-dated single-fetus ewes were selected to induce diaphragmatic hernia. Fetal lambs were divided proportionally into 2 groups, namely group 1, diaphragmatic hernia and tracheal ligation (TL group), and group 2, diaphragmatic hernia only (NL gr...

PURPOSE Characterization of the structural changes occurring in the pulmonary arteries resulting from surgically produced congenital diaphragmatic hernia in rabbits, with particular emphasis on the preventive effects of prenatal tracheal ligation or administration of intra-amniotic dexamethasone or surfactant. METHODS Twenty rabbit fetuses underwent surgical creation of a left-sided congenita...

Tracheoinnominate artery fistula is known as a potentially fatal complication for patients who depend on tracheostomy or tracheoesophageal diversion. Since the bleeding from a TIF is often difficult to control, preventative procedures are recommended to avoid this complication. An 11-year-old girl with hypoxic-ischemic encephalopathy and scoliosis developed tracheal stenosis caused by compressi...

abstract   background: iatrogenic airway injury after endotracheal intubation and tracheotomy remains a serious clinical problem. in this study we reviewed post-intubation and traumatic tracheal stenosis in 47 patients with a special attention to the cause, hense surgical treatment of the stenosis was performed and the results compared with the literatures.   methods: since february 1995 throug...

INTRODUCTION Ischemic heart disease is a major public health problem in western countries. Appropriate animal experimental models of chronic myocardial infarction is an essential first step in order to investigate and develop new therapeutic interventions. AIM The aim of this study was to find an optimal place for a coronary artery ligation to induce an optimal chronic myocardial infarction a...

Studies on lung morphogenesis have indicated a role of homeobox( Hox) genes in the regulation of lung development. In the present study, we attempted to modulate the synthesis of Hoxb5 protein in cultured murine fetal lungs after mechanical or chemical stimuli. Murine fetuses at gestational day 14 (GD14) were removed from pregnant CD-1 mice, and lungs were excised and cultured for 7 days in BGJ...

RATIONALE The role of the patent ductus arteriosus in the development of chronic lung disease in surfactant-treated premature newborns remains unclear. OBJECTIVE To examine the effects of ductus ligation on cardiopulmonary function and lung histopathology in premature primates. METHODS Baboons were delivered at 125 d, (term = 185 d) treated with surfactant, and ventilated for 14 d. Serial e...

introduction: tracheal stenosis is normally caused by trauma, infection, benign and malignant tumors, prolonged intubation or tracheostomy. the best treatment for tracheal stenosis is resection and anastomosis of trachea. yet the major surgical complication of tracheal surgery is postoperative stenosis. the goal of this paper is to study the result of tracheal stenting as a replacement therapy ...

Cranial nerve injuries are well-recognized complications of laryngoscopy and tracheal intubation and face mask ventilation. Recently, these have also been reported in association with extraglottic airway devices. Its diagnosis is clinical and it has a good prognosis, with resolution of the symptoms within a few weeks to months. The frequency of cranial nerve injuries can be reduced by avoiding ...