due to an adenocarcinoma of the right upper lobe with infiltration of the main bronchus a 49-years-old female patient underwent an upper bilobectomy with sleeve resection. after two completed chemotherapy bouts and signs of sepsis another thoracotomy was inevitable.  as a complicating factor a supracarinal, necrotic and perforating lesion of the trachea appeared. the defect can be initially rep...

BACKGROUND Tracheal necrosis is a severe complication of total pharyngolaryngectomy (TPL). The purpose of this retrospective study was to identify risk factors for tracheal necrosis after TPL. METHODS We performed a retrospective chart review of 177 patients who had undergone TPL. The preoperative, operative, and postoperative variables were examined, and possible risk factors for tracheal ne...

Total thyroidectomy involving the adjacent structures of the trachea can cause tracheal damage such as early tracheal necrosis. The authors describe the first case of anterior tracheal necrosis following total thyroidectomy treated using vacuum-assisted closure device. After two weeks of VAC  therapy, there was no evidence of ongoing infection and the trachea was partially closed around a trach...

its adjacent structures can cause tracheal damage such as ulceration of the mucosa, tracheal stenosis, tracheoesophageal fistula, tracheomalacia and neck abscess. We describe a case of upper tracheal necrosis as a complication of total thyroidectomy in a hyperthyroid patient, highlighting some of the difficulties presented by a thyrotoxic goitre, which, to our knowledge has not been reported be...

Tracheal rupture is a rare condition, and its most common cause is head and neck injury. Nontraumatic disruption of the anterolateral fibrocartilaginous trachea is an exceptional complication following thyroidectomy with few cases reported in literature. We report a case of upper tracheal necrosis arising 15 days after uneventful total thyroidectomy and resulted in pneumomediastinum and subcuta...

Recent studies have implicated a role for tumour necrosis factor-alpha (TNFalpha) in the development of the asthmatic reaction. In this study, we examined the influence of TNFalpha on isotonic contraction of tracheal smooth muscle of the guinea-pig in vitro in response to methacholine. Tracheal rings were incubated with recombinant human (rh)TNFalpha (3x10(-11) M) for 30 min, and concentration-...

There are significant complications associated with endotracheal intubation. Massive tracheal necrosis secondary to tracheoesophageal space abscess developed in a 71-year-old man during mechanical ventilation. Elevated endotracheal tube cuff pressures, sepsis, hypotension, and other risk factors predispose to this disastrous consequence.

abstract   background: iatrogenic airway injury after endotracheal intubation and tracheotomy remains a serious clinical problem. in this study we reviewed post-intubation and traumatic tracheal stenosis in 47 patients with a special attention to the cause, hense surgical treatment of the stenosis was performed and the results compared with the literatures.   methods: since february 1995 throug...