Since the establishment of the inflammatory basis of atherosclerosis, several pro- or anti-inflammatory agents have been examined as potential mediators of the biochemical pathways of lesion formation. Interleukin (IL)-8 was first characterized in 1987. Since then, knowledge regarding its role in leucocyte trafficking and activation has advanced rapidly, especially in the field of cardiovascula...

In eukaryotes, vesicle trafficking is regulated by the small monomeric GTPases of the Rab protein family. Rab11, (a subfamily of the Ypt/Rab gene family) an evolutionarily conserved, ubiquitously expressed subfamily of small monomeric Rab GTPases, has been implicated in regulating vesicular trafficking through the recycling of endosomal compartment. In an earlier communication, we have shown th...

Technology is often highlighted in popular discourse as a causal factor significantly increasing sex trafficking. However, there paucity of robust empirical evidence on trafficking and the extent to which technology facilitates it. This has not prevented proliferation beliefs that essential for disrupting or even ending Big data analytics anti-trafficking software are used this context produce ...

STUDY OBJECTIVE Our aim was to assess: (1) medical trainee and practicing physician awareness about domestic sex trafficking of minors; and (2) whether respondents believe that awareness of trafficking is important to their practice. DESIGN AND SETTING We designed an anonymous electronic survey, and a convenience sample was collected from June through October 2013. PARTICIPANTS Voluntary pa...

Acrosome plays an integral role during fertilization and its absence in individuals with globozoospermia leads to failure of in vitro fertilization (IVF) and oocyte activation post-intracytoplasmic sperm injection (ICSI). A variety of processes, organelles and structures are involved in acrosome biogenesis including, trans-Golgi network (TGN), acroplaxome and cellular trafficking. This review a...

cytomegalovirus is the leading viral cause of congenital disease, often producing serious neurological deficits. cmv attacks the developing central nervous system (cns) resulting in serious brain disorders that include microencephaly, epilepsy, deafness, microgyria, mental retardation, sensory loss, motor problems, and psychiatric disturbances. in addition, cmv is a clinically important opportu...

new millennium began when half of world population is living in the cities. predictions represent that the proportion of citizenship will reach to 65 percent by 2050. one the phenomena affected by living in the cities is citizenship. citizenship phenomenon is one of the phenomena that in in the era of social political evolution in the world have received much attention. presentation of theories...

Abstract. Indonesia is the third largest supplier country in world for fishery workers. Crews who work on national and foreign vessels are often victims of human trafficking fishing industry. In this study, cases were taken regarding crimes against Indonesian crew members Long Xing 629 ship, form persons exploitation Human that occurs industry aims to exploit workers, case members. Trafficking ...

background rheumatic diseases are chronic diseases, which may be associated with severe and debilitating pain. objectives the purpose of this study was to examine the prevalence of tobacco and opioid use among rheumatic patients. patients and methods in this cross-sectional study, 1042 patients referred to a major rheumatology clinic of kerman city, in south east of iran, were interviewed. pati...

We have detected new clues to the composition and function of "Transfer Factor" using the direct Leucocyte Migration Inhibition (LMI) test as an in vitro assay of Dialysates of Leucocyte Extracts (DLE). This approach has revealed two opposing antigen-specific activities to be present in the same > 3500 < 12,000 DA dialysis fraction - one activity is possessed of Inducer/Helper function (Inducer...