Aim. We aimed to evaluate levels of transforming growth factor β1 (TGF-β1) in the serum, lymph nodes, and primary tumour patients with colorectal cancer. Materials Methods. Here we enrolled 44 cancer 25 benign tumours colon admitted Chita Regional Cancer Centre 2019-2020. The control group included injury. concentration TGF-β1 homogenate was measured by flow cytometry (CytoFlex LX analyzer LEGE...

Transforming Growth Factor β1 (TGF-β1) is a well-known neuroprotective and neurotrophic factor demonstrated to play a role in synaptic transmission. However, its involvement in physiological mechanisms underlying synaptic plasticity and memory at hippocampal level has not been thoroughly investigated. Here, we examine the role of TGF-β1 in hippocampal long-term potentiation (LTP) and memory in ...

Objective: To investigate effect from total glucosides of paeony on protein expression of nuclear factorκB and transforming growth factor β1 in liver tissue of rats with hepatic fibrosis. Methods: Healthy SD rats were randomly chosen and divided into normal group (group N), model group (group M) and TGP high, medium, low dose treatment group (T1-T3). Except the normal group, all the groups rece...

pulmonary fibrosis is a progressive disease of the lungs, which leads to death in human. it has been suggested that transforming growth factor beta 1 (tgf-β1) together with oxidative stress play a central role in the pathogenesis of the ailment. the objective of this study was to evaluate the possible curative effects of black radish, raphanus sativus l . var niger (rsn) on bleomycine (blm) -in...

background: during antigen capture and processing, mature dendritic cells (dc) express large amounts of peptide-mhc complexes and accessory molecules on their surface. dc are antigen-presenting cells that have an important role in tolerance and autoimmunity. the transforming growth factor-beta1 (tgf-β1) cytokine has a regulatory role on the immune and non-immune cells. the aim of this study is ...

​Background and purpose: Glycation products, oxidative stress, and inflammation contribute to the development of diabetic nephropathy (DN) due to the elevation of transforming growth factor-β1 (TGF-β1). This study aimed at investigating the effect of Cysteine (Cys) on TGF-β in DN rat model. Materials and methods: In this experimental study, 40 male Wistar rats were randomly divided into four g...

Silver salts and nanosilver (NS) are the common antimicrobial used in the treatment of chronic wounds, so they are important to assess their dermal toxicity. Therefore, in this study, the possible dermal toxicity of NS particles and silver nitrate (AgNO3), was tested by determining the serum level of transforming growth factor-β1(TGF-β1) and study on of mouse skin tissue. In this stu...