نتایج جستجو برای: triterpenes
تعداد نتایج: 1865 فیلتر نتایج به سال:
AIMS Pentacyclic triterpenes are a group of molecules with promising anticancer potential, although their precise molecular target remains elusive. The current work aims to investigate the antiproliferative and associated mechanisms of triterpenes in breast cancer cells in vitro. MAIN METHODS Effect of triterpenes on cell cycle distribution, ROS and key regulatory proteins were analyzed in th...
Triterpenes, thirty-carbon compounds derived from five-carbon isoprene units, are among the largest and diverse classes of natural products. To date, over 20,000 distinct triterpene structures having more than 100 skeletal variations are indentified from natural sources. The majority of this triterpene diversity is found within the plant kingdom. Plants often accumulate triterpenes in their gly...
Background Pluchea quitoc DC. (Asteraceae), a medicinal plant known as "quitoco," "caculucage," "tabacarana" and "madre-cravo," is indicated for inflammatory conditions such as bronchitis, arthritis, and inflammation in the uterus and digestive system. Objective This study evaluated the analgesic and anti-inflammatory activities of the triterpenes compounds obtained from P. quitoc aerial part...
mode and two-dimensional nuclear magnetic resonance spectroscopy allowed us to purify and determine structures of triterpenes 1–4 in pedunculate oak heartwood (8). Our main interests are in the acid triterpene content of oak heartwoods used in cooperage, their astringent properties, and their occurrence in wines and spirits. In this article, we report a highly sensitive and quantitative detecti...
Pentacyclic triterpenes are produced by arrangement of squalene epoxide. These compounds are extremely common and are found in most plants. There are at least 4000 known triterpenes. Many triterpenes occur freely but others occur as glycosides (saponins) or in special combined forms. Pentacyclic triterpenes have a wide spectrum of biological activities and some of them may be useful in medicine...
Ganoderma luncidum (Leyss. ex Fr.) Karst. (GLK) has been used traditionally for the prevention and treatment of cancers or tumors for a long time in Traditional Chinese Medicine. The triterpenes as main effective components of GLK have been found to be beneficial for the efficacy. The purpose of this study was to examine the anti-lung cancer activity of triterpenes of GLK in vitro and in vivo a...
In order to determine on the anti-complement activity of triterpenes, following eleven triterpenoides were isolated from the fruits of the Zizyphus jujuba MILL: ceanothane-type triterpenes: colubrinic acid (1), zizyberenalic acid (11); lupane-type triterpenes: alphitolic acid (2), 3-O-cis-p-coumaroyl alphitolic acid (3), 3-O-trans-p-coumaroyl alphitolic acid (4), betulinic acid (7), betulonic a...
a review of the publications in traditional medicine indicates that the root of glycyrrhiza glabra l., fabaceae, is recommended for treatment of epilepsy. as a renewable source, the leaves of g. glabra var. glandulifera growing in iran were examined for possible anticonvulsant activity. the anticonvulsant activity of the leaves’ ethanol extract and dichloromethane, f1, n-hexane, f1a, and methan...
Three new dammarane triterpenes, cereotagaloperoxide, cereotagalol A, and cereotagalol B, together with four known dammarane triterpenes, an oleanane triterpene, and 13 known lupane triterpenes were isolated from the hypocotyls and fruits of Ceriops tagal. The structures of 1-3 were characterized on the basis of their spectroscopic data.
SCOPE Inhibiting human neutrophil elastase (HNE) is a promising strategy for treating inflammatory lung diseases, such as H1N1 and SARS virus infections. The use of sivelestat, the only clinically registered synthesized HNE inhibitor, is largely limited by its risk of organ toxicity because it irreversibly inhibits HNE. Therefore, potent reversible HNE inhibitors are promising alternatives to s...
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