Tuberculous pleurisy is the most common form of extrapulmonary tuberculosis in Korea. Tuberculous pleurisy presents a diagnostic and therapeutic problem due to the limitations of traditional diagnostic tools. There have been many clinical research works during the past decade. Recent studies have provided new insight into the tuberculous pleurisy, which have a large impact on clinical practice....

BACKGROUND A high concentration of hyaluronic acid in pleural fluid is suggestive of malignant mesothelioma. However, a relatively high concentration of hyaluronic acid was also seen in the pleural fluid of patients with benign inflammatory diseases. To show the utility of measuring hyaluronic acid levels in pleural fluid to diagnose tuberculous pleurisy, we compared the clinical features and l...

cases were reported in 2015, which accounted for 9.6% of the 32,181 new TB cases and 46.6% of the 6,631 extrapulmonary TB cases (Table 1). Tuberculous pleurisy is the most common form of extrapulmonary tuberculosis (TB) and is the main cause of pleural effusion in Korea. In Korea, 3,089 new tuberculous pleurisy Progression of Tuberculous Pleurisy: From a Lymphocyte-Predominant Free-Flowing Effu...

BACKGROUND AND OBJECTIVE The diagnosis of tuberculous pleurisy by analysis of pleural fluid using standard diagnostic tools is difficult. Recently, T-cell interferon-γ release assays (IGRA) have been introduced for the diagnosis of tuberculous pleurisy. The aim of the present meta-analysis was to establish the overall diagnostic accuracy of IGRA on both pleural fluid and peripheral blood, for d...

PURPOSE Tuberculous pleurisy is the most frequent extrapulmonary manifestation of tuberculosis. In spite of adequate treatment, pleural fibrosis is a common complication, but the mechanism has not been elucidated. This study is to determine whether epithelial to mesenchymal transition (EMT) of mesothelial cells occurs in tuberculous pleurisy. MATERIALS AND METHODS Normal pleural mesothelial c...

BACKGROUND Conventional tests are not always helpful in making a diagnosis of tuberculous pleurisy. Many studies have investigated the usefulness of adenosine deaminase (ADA) in pleural fluid for the early diagnosis of tuberculous pleurisy. We conducted a meta-analysis to determine the accuracy of ADA measurements in the diagnosis of tuberculous pleurisy. METHODS After a systematic review of ...

BACKGROUND Conventional tests are not always helpful in making a diagnosis of tuberculous pleurisy. Many studies have investigated the usefulness of interferon (IFN)-gamma measurements in pleural fluid for the early diagnosis of tuberculous pleurisy. We conducted a metaanalysis to determine the accuracy of IFN-gamma measurements in the diagnosis of tuberculous pleurisy. METHODS After a system...

pleural effusions, as Dr. Kiropoulos mentioned. Momi et al2 and Hamed et al3 measured VEGF levels both in the serum and pleural fluid of tuberculous pleurisy patients. They found elevated VEGF levels both in the serum and pleural fluid of tuberculous pleurisy patients compared with congestive heart failure patients. In congestive heart failure patients, both of the studies reported higher VEGF ...

The T lymphocyte-mediated immune response to Mycobacterium tuberculosis infection in the parietal pleura of patients with tuberculous pleurisy is unknown. The aim of this study was to investigate the immune response in the parietal pleura of tuberculous pleurisy compared with nonspecific pleuritis. We have measured the numbers of inflammatory cells particularly T-cell subsets (Th1/Th2/Th17/Treg...

The series comprised 37 patients admitted to hospital for the diagnostic evaluation of one-sided or bilateral pleurisy. Patients with malignancies of extrapulmonary tissues were not included. The diagnosis of pleurisy was based on clinical, laboratory, and radiological findings. The patients were divided into three groups according to the final diagnosis: (a) those with tuberculous pleurisy, (b...