background: early detection is a key to survival for gastric cancer. molecular markers such as mirna (microrna) can have great importance in the early diagnosis of gastric cancer. expression of mir-21 and mir-221 are deregulated in many types of human cancers. this study aimed to investigate the differences in mirna expression patterns within the iranian population. methods: total rna was extra...

immunohistochemical demonstration of tumor-associated markers may be valuable as an adjunct to conventional histology for determination of malignancy development in oral mucosal diseases. accordingly, the present study determined the distribution of some important tumor markers such as heat shock proteins (hsp), fibroblast growth factors (fgf) and transferrin receptors (tf-r) in 22 samples of p...

background: the gold standard for detection of bladder cancer is cystoscopy, which is an invasive and complicated procedure. our study was conducted to find a tumor marker with high specificity, sensitivity, and accuracy for the diagnosis of bladder cancer. methods: serum samples were collected from 58 bladder cancer patients and 60 healthy control subjects. levels of lipid-bound sialic acid (l...

Background: Solitary fibrous tumor (SFT) is a mesenchymal tumor which is most commonly seen in the pleura; however it can be seen in other organs such as the meninge, gastrointestinal tract, soft tissue, bone, and skin. SFT should be differentiated from other mesenchymal tumors in these organs. Immunohistochemistry plays a pivotal role for the histopathologic diagnosis...

salivary diagnostics has fascinated many researcheres and has been tested as a valuable tool in the diagnosis of many systemic conditions and for drug monitoring. advances in the field of molecular biology, salivary genomics and proteomics have led to the discovery of new molecular markers for oral cancer diagnosis, therapeutics and prognosis. oral cancer is a potentially fatal disease and the ...

background: solitary fibrous tumor (sft) is a mesenchymal tumor which is most commonly seen in the pleura; however it can be seen in other organs such as the meninge, gastrointestinal tract, soft tissue, bone, and skin. sft should be differentiated from other mesenchymal tumors in these organs. immunohistochemistry plays a pivotal role for the histopathologic diagnosis of this tumor. currently,...

results: the only significant difference was the older age of the malignant group vs. benign group (p = 0.001) regarding demographic findings. as concerns the clinical symptoms, presence of abdominal discomfort in pre-diagnosis period was the only significant parameter in malignant group (p = 0.001). additionally, data analysis of patients as a total group showed that specificity (96.4%), posit...

background: solid ameloblastoma (sab) is an invasive tumor which infiltrates adjacent normal tissues. adenomatoid odontogenic tumor is a noninvasive tumor and never infiltrates surrounding normal tissues. the purpose of this study was to determine the biological behavior of these two epithelial odontogenic neoplasm by detecting ki-67 and bcl-2, which are mitotic and anti apoptotic markers respe...