AIMS Inflammation, endothelial cell function and the coagulation system have been demonstrated to be involved in the onset and course of unstable angina. Whether a proinflammatory state independently determines outcome is unknown and has not been determined yet in a clinically well defined study population of consecutive patients admitted with unstable angina. METHODS AND RESULTS Markers of i...

introduction: several studies have shown the independent association of high plasma c - reactive protein (crp) levels with adverse prognosis in patients with acute myocardial infarction (mi). the aim of this study was to assess the prognostic value of quantitative crp (q-crp) to predict mi in patients with unstable angina. materials & methods: this cohort study was carried out between december ...

441 Abstract: Cardiac troponin T (TnT) is a regulatory contractile protein not normally found in blood. Minor elevations of TnT in patients with unstable angina have been associated with an increased risk of subsequent death or Acute Myocardial Infarction (AMI). We used a neewly developed enzyme immunoassay for TnT to determine whether its presence in the serum of patients with unstable angina ...

In the 1980s, our group published a series of articles using invasive angiography (ICA) to investigate the pathogenesis of unstable angina and acute myocardial infarction.1–5 In individuals in whom an angina-producing lesion could be assessed angiographically and the vessel was 100% occluded at the time of angiography, the qualitative morphology of these lesions was different from that of lesio...

STUDY OBJECTIVE To test the hypothesis that the active coronary endothelial lesions in unstable angina raise the endothelin concentration in coronary venous blood. DESIGN Systemic and coronary venous blood samples were obtained from unselected patients with the clinical syndromes of either stable or unstable angina at the time of cardiac catheterisation and coronary arteriography. Control ven...

Objective: Inflammation along with oxidative stress plays an important role in the development, progression, instability and rupture of coronary atherosclerotic plaques. Several studies introduced curcumin (diferuloylmethane) as a wonderful chemical in Curcuma longa<span style="font-size: m...

Dear editor Regarding the duration of supplement therapy in our study which has been published in the Avicenna J Phytomed, 2019; 9(1): 1-9, “The effects of curcumin on the prevention of atrial and ventricular arrhythmias and heart failure in patients with unstable angina” (Dastani et al., 2019),  some critical flaws has been mentioned. Primarily, we are grateful for the consi...

The degree of reduction in heart rate variability (HRV) after myocardial infarction has been shown to have prognostic significance, but HRV has not been studied extensively in patients with unstable angina. We assessed spectral and nonspectral measurements of HRV in 52 patients with unstable angina, 52 patients with acute myocardial infarction, and 41 normal subjects. The spectral bands of 0.04...