OBJECTIVE To more clearly elucidate the association between prostate volume and Gleason score (GS) upgrading. PATIENT AND METHODS We reviewed 451 patients with prostate cancer with a GS of 6 on biopsy, who underwent radical prostatectomy without neoadjuvant treatment. As a preoperative variable, we assessed the independent effect of prostate volume on GS upgrading. To evaluate the association...

OBJECTIVE To examine the risk factors associated with the odds of extreme Gleason upgrading at radical prostatectomy (RP) (defined as a Gleason prognostic group score increase of ≥2), we utilized a large, population-based cancer registry. MATERIALS AND METHODS The Surveillance, Epidemiologic, and End Results database was queried (2010-2011) for all patients diagnosed with Gleason 3 + 3 or 3 +...

Determination of Fuhrman grade (FG) on biopsies of renal masses is relatively inaccurate, being prone to underestimating the true grade as ascertained from surgical specimens. This study evaluated whether anatomical features of tumors could predict tumor upgrading between core biopsies and surgical specimens. We prospectively enrolled 249 patients undergoing surgical resection of solid renal ma...

This paper begins with a discussion of the role played by upgrading in the promotion of sustainable growth. Upgrading is discussed in two different contexts, that of industrial clusters and that of global value chains (GVCs). Drawing on global and African experiences, the paper addresses the upgrading agenda required to enable dynamic clusters to meet both domestic needs and progressively also ...

Despite the accelerated pace at which progress in wireless technologies occurs, it is not uncommon to observe that some Mobile Operators (MOs) do not upgrade their mobile services, while their competitors adopt the newest technological standards. This paper proposes an explanation for this apparent paradox by means of a formal theoretical model that acknowledges demand heterogeneity in a qualit...

The eccentricity lowering problem is to reduce the eccentricity of a communication network within a given bound, by upgrading some nodes (i.e., shrinking the lengths of the edges linking to such nodes), where we want to minimize the required cost. We consider two types of node-upgrading strategies; i.e., the continuous upgrading and the discrete upgrading, where the improvement under the first ...

Objective. To determine whether initial biopsy performed by community or academic urologists affected rates of Gleason upgrading at a tertiary referral center. Gleason upgrading from biopsy to radical prostatectomy (RP) is an important event as treatment decisions are made based on the biopsy score. Materials and Methods. We identified men undergoing RP for Gleason 3 + 3 or 3 + 4 disease at a t...

Informal settlement upgrading is widely recognized for enhancing shelter and promoting economic development, yet its potential to improve health equity is usually overlooked. Almost one in seven people on the planet are expected to reside in urban informal settlements, or slums, by 2030. Slum upgrading is the process of delivering place-based environmental and social improvements to the urban p...

this research, in addition to survey the existing data on the quality of sahebgharanieh wastewater treatment plant's effluent in the previous years, by runing a three months monitoring stage, studies the conditions of the final settling and aeration basin and the variations of the influent and effluent quantity and quality in removing of major pollutants (bod, cod, tss), while scrutinizing the ...

What is the scope for local upgrading strategies where producers operate in global value chains? The literature on industrial clusters emphasises the role of inter-firm co-operation and local institutions in enabling upgrading. The value chain literature focuses on the role of global buyers and chain governance in defining upgrading opportunities. This paper argues that clusters are inserted in...