Reliability analysis of fatigue lifetime design has two assignments: a. To forecast fatigue lifetime of the structure on given reliability level, b. To evaluate reliability level of the structure on given service conditions, material features and designing dimensions. It aims at evaluating the structure’s designing quality and providing a basis for designing improvement or manufacturing. At mea...

BACKGROUND The design complexity of critical care ventilators (CCVs) can lead to use errors and patient harm. In this study, we present the results of a comparison of four CCVs from market leaders, using a rigorous methodology for the evaluation of use safety and user experience of medical devices. METHODS We carried out a comparative usability study of four CCVs: Hamilton G5, Puritan Bennett...

Aquaeous methanolic extracts of pomegranate peel (Punica granatum) and veratrum (Veratrum album) were evaluated for their effects supplementation in fish diets on oxidative status, digestive enzymes immunity rainbow trout fingerlings (Oncorhynchus mykiss). Three different concentrations 250 (P250), 500 (P500) 1000 (P1000) mg kg-1 (V250), (V500) (V1000) added to the diet fed these 60 days over a...

BACKGROUND Even though it is not a common practice, an external filter to the expiratory limb of the breathing circuit may protect the expiratory valve from water saturation in case of nebulization, or from the environment in case of lung infection with multi-drug-resistant micro-organisms or H1N1 influenza. METHODS We added an external filter to the expiratory limb and measured tidal volume ...

The postprandial reduction in blood pressure (BP) is triggered by the interaction of nutrients with the small intestine and associated with an increase in splanchnic blood flow. Gastric distension may attenuate the postprandial fall in BP. The aim of this study was to determine the effects of differences in intragastric volume, including distension at a low (100 ml) volume, on BP and superior m...

Multidrug resistance (MDR) genes, which are ATP-binding cassette family genes, encode the cell surface glycoprotein, P-glycoprotein, which functions as an energy-dependent drug efflux pump. Two relevant human genes, PGY1 and PGY3, are located on human chromosome 7, and three relevant mouse genes, mdr1a, mdr1b, and mdr2, are located on mouse chromosome 5. An LMD1 cell line was established after ...

Often ABR threshold testing employs clicks to assess high-frequency hearing, and low-frequency tone bursts to assess low-frequency sensitivity. While a maturation effect has been shown for click stimuli, similar data are lacking for low-frequency toneburst stimuli. Thus, 305 infants ranging in conceptional age (CA) from 33 weeks to 74 weeks were tested. Absolute latencies were measured for wave...

Determining the usability of mechanical ventilator interfaces is vital in ensuring correct usage under critical procedures that can place patients’ health danger. Heuristic evaluation has been used to evaluate many different areas, including medical devices. The objective this study a using heuristic method. simulator (Drager's Evita V500) was performed Evaluation System Checklist (HESC). Three...

The surface of Mars consists of an old, heavily cratered and elevated southern hemisphere and younger, resurfaced and depressed northern hemisphere, a feature often termed the crustal dichotomy. The global crustal structure [Zuber et al., 2000] revealed by topography and gravity data from the Mars Global Surveyor spacecraft, and the possible late formation of the boundary zone between the hemis...