BACKGROUND Embryo transfer to a developed endometrium is an important prognostic factor in frozen-thawed embryo transfer cycle outcome. Vaginal estrogen, such as Vagifem vaginal tablets and Premarin vaginal cream, is a regimen used for the patients with refractive endometria. OBJECTIVE Our objective was to compare the effects of Vagifem and Premarin on the endometrial thickness of the patient...

BACKGROUND Atrophic vaginitis is a disease, which affects up to 50% of postmenopausal women. This study compared the effectiveness and user-friendliness of Vagifem (an estradiol vaginal tablet) and vaginal estrogen cream in the treatment of atrophic vaginitis. MATERIALS AND METHODS One hundred and sixty postmenopausal women with symptoms of atrophic vaginitis were randomly divided into two gr...

background: atrophic vaginitis is a disease, which affects up to 50% of postmenopausal women. this study compared the effectiveness and user-friendliness of vagifem (an estradiol vaginal tablet) and vaginal estrogen cream in the treatment of atrophic vaginitis. materials and methods: one hundred and  sixty postmenopausal women with symptoms of atrophic  vaginitis were randomly divided into two ...

Vulvovaginal atrophy [VVA] is defined as inflammation of the vaginal epithelium due to atrophy secondary to decreased levels of circulating estrogen. There is currently only one approved method for the treatment of VVA, and that is the administration of exogenous estrogens. Overall, the ideal VVA treatment must have benefits, minimize risks, and enhance compliance in the patient while optimizin...

BACKGROUND Aromatase inhibitors (AI) are increasingly used in early breast cancer and there is a growing interest in associated long-term side-effects of profound estrogen suppression. Urogenital side-effects due to atrophic vaginitis are often managed with vaginal estrogen preparations. These are generally perceived to result in minimal systemic absorption of estrogen. We followed serum estrad...