نتایج جستجو برای: vascular endothelial growth factor a

تعداد نتایج: 13882522  

Journal: :European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2007
Mika Lahtinen Pontus Blomberg Giedrius Baliulis Fredrik Carlsson Harry Khamis Vitas Zemgulis

OBJECTIVES Small-diameter synthetic vascular graft performance is inferior to autologous vein grafts. This study tested the hypotheses that local in vivo administration of plasmids encoding for human vascular endothelial growth factor (VEGF), or co-administration of plasmids encoding for human vascular endothelial growth factor/plasmids encoding for fibroblast growth factor-2 in the tissues sur...

Background and Objectives: Cigarette smoke contains carcinogenic compounds, including nicotine-derived nitrosamine ketone (NNK), which can activate vascular endothelial growth factor (VEGF) and increase the inflammation of the lung. Since the Nigella sativa plays an important role in treating cancer through the modification of cellular signaling pathways, the purpose of this study was dete...

Journal: :Circulation 2005
Pia Leppänen Suvi Koota Ivana Kholová Jonna Koponen Christina Fieber Ulf Eriksson Kari Alitalo Seppo Ylä-Herttuala

BACKGROUND The role of vascular endothelial growth factors (VEGFs) in large arteries has been proposed to be either vasculoprotective or proatherogenic. Because VEGF family members are used for human therapy, it is important to know whether they could enhance atherogenesis. We tested the effects of the members of the VEGF gene family on atherogenesis in LDL-receptor/apolipoprotein (apo) B48 dou...

Journal: :Investigative ophthalmology & visual science 2002
Antonella N Witmer Harriet G Blaauwgeers Herbert A Weich Kari Alitalo Gijs F J M Vrensen Reinier O Schlingemann

PURPOSE The vascular endothelial growth factor (VEGF) family is involved in vascular leakage and angiogenesis in diabetic retinopathy (DR) in the eye, but may also have physiological functions. Based on the hypothesis that differential VEGF receptor (VEGFR) expression in the retina is an important determinant of effects of VEGF, this study was conducted to investigate VEGFR expression in the di...

Journal: :Scientific journal of Kurdistan University of Medical Sciences 2022

The Effect of Silybinin on the Expression Vascular Endothelial Growth Factor (VEGF) and Integrin-linked kinase (ILK) in Olfactory Ensheathing Cells under Normal High Glucose Conditions

2014
Tetiana Manhylova

Objective: to compare level of the main cytokines induced by ischemia (vascular endothelial growth factor and erythropoietin) in patients with first grade arterial hypertension with and without obesity and in normotesive persons. Methods. 79 patients with first grade arterial hypertension (50 with accompany obesity) were examined. 54 individuals with optimal or normal blood pressure were includ...

Journal: :Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009
Yelena Krupitskaya Heather Wakelee

New blood vessel formation (angiogenesis) is essential for the processes of tumor growth, invasion, and metastatic dissemination,1 and agents that inhibit this pathway, such as bevacizumab, have proven anticancer activity.2 Interactions between tumorand stroma-produced vascular endothelial growth factor (VEGF) ligands (particularly VEGF-A) and receptors (particularly VEGF receptor [VEGFR] 2) ar...

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