The no reflow phenomenon is a feared complication in Percutaneous Coronary Intervention (PCI) procedures including elective as well primary PCI (Percutaneous Intervention), and results worse prognosis. A number of etiological factors are involved pathogenesis phenomenon. These include distal athero embolization, ischemic reperfusion injury, microvascular spasm endothelial dysfunction. treatment...

results there was a real faster response in the first group; while groups 3 and 4 had the slowest responses to treatment. rates of responsiveness seemed to have no significant difference between the groups, but side effects were significantly much frequent in the first group. conclusions intralesional triamcinolone acetonide with cryotherapy showed the most efficacies with more adverse effects,...

BACKGROUND  One of the weaknesses of recovering the skin defects by tissue expander device is that it needs relatively long time and it has complications. Since verapamil gel reduces the production of these capsules around silicone prosthesis and reduces the formation of collagen in the capsule areas. The aim of this study was to examine the effect of verapamil gel on efficiency of tissue...

Calcium, through its various channels involves in local, spinal and supra-spinal transmission of pain. In the present study, we investigated the separate and combined treatment effects of verapamil (a calcium channel blocker), morphine (an opioid agonist) and naloxone (an opioid antagonist) on pain in the orofacial region of rats. Orofacial pain was induced by subcutaneous (SC) injection of for...

Autoimmune pancreatic β-cell loss and destruction play a key role in the pathogenesis development of type 1 diabetes, with prospective increased risk for developing micro- macrovascular complications. In this regard, orally administrated verapamil, calcium channel antagonist, usually intended use as an anti-arrhythmic drug, has previously shown potential beneficial effects on preservation new-o...

Using 10 isolated, blood-perfused canine atrial, and ventricular preparations, the effects of d- and l-verapamil on SA nodal pacemaker activity and contractility were investigated. l-verapamil and d-verapamil produced dose-related negative chronotropic and inotropic effects in all experiments. l-verapamil was approximately 10 time more potent than d-verapamil both in inotropism and chronotropis...

the role of opioid receptor and voltage dependent calcium channels on the kindling induced by the convulsant pentylenetetrazole (ptz) were investigated in the rats. experiment involved 24 rats which were divided into four groups. kindling was established with ptz in subconvulsive dose (37.5 mg/kg i.p.) every 48 h and effects were observed within 20 min using five-point scoring system. all anima...

The efficacy of i.v. and oral verapamil was studied in 28 patients with supraventricular tachycardia (SVT). Verapamil (5-10 mg i.v.) terminated SVT in all six patients with atrioventricular nodal (AVN) reentrant tachycardia. In all patients verapamil prolonged antegrade but did not affect retrograde AVN conduction time. Two patients had associated sinus nodal reentrant tachycardia that persiste...

BACKGROUND The effect of verapamil on long-term tachycardia-induced atrial electrical remodeling has not been reported. METHODS AND RESULTS Forty-eight dogs were randomly divided into verapamil and control groups. The dogs in the verapamil group received verapamil 120 mg every day, those in the control group did not receive verapamil. Atrial effective refractory period (AERP), inducibility of...