The Whole of Government (WG) approach is increasingly seen as an imperative for delivering coherent and integrated policies, joined up and seamless services, and integrated program management in government. Although no generic WG framework currently exists, there are reported cases of WG initiatives by different governments. Grounded in existing theories, frameworks and cases related to inter-o...

The potent activity of Wnt/Wingless (Wg) signals necessitates sophisticated mechanisms that spatially and temporally regulate their distribution and range of action. The two main receptor components for Wg - Arrow (Arr) and Frizzled 2 (Fz2) - are transcriptionally downregulated by Wg signaling, thus forming gradients that oppose that of Wg. Here, we analyze the relevance of this transcriptional...

abstract in this research, four meteorological set of data including maximum temperature, minimum temperature, precipitation and radiation from echo-g, under a1scenario have been used for climate change detection over south khorasan. echo-g is a general circulation model that currently is used in hamburg university and korea meteorological research institute. in this research climate change ass...

BACKGROUND Korean ginseng is a well-known medicinal herb that has been widely used in traditional medicine to treat various diseases, including asthma. Ginseng can be classified as white ginseng (WG) or red ginseng (RG), according to processing conditions. In this study, the authors compared the efficacies of these two ginseng types in a mouse model of acute asthma. METHODS To produce the acu...

Recommendations for whole-grain (WG) intake are based on observational studies showing that higher WG consumption is associated with reduced CVD risk. No large-scale, randomised, controlled dietary intervention studies have investigated the effects on CVD risk markers of substituting WG in place of refined grains in the diets of non-WG consumers. A total of 316 participants (aged 18-65 years; B...

background: municipal solid waste (msw) is the natural result of human activities. msw generation modeling is of prime im­portance in designing and programming municipal solid waste management system. this study tests the short-term pre­diction of waste generation by artificial neural network (ann) and principal component-regression analysis. methods: two forecasting techniques are presented in...

The potent activity of Wnt/Wingless (Wg) signals necessitates sophisticated mechanisms that spatially and temporally regulate their distribution and range of action. The two main receptor components for Wg – Arrow (Arr) and Frizzled 2 (Fz2) – are transcriptionally downregulatedbyWgsignaling, thus forminggradients that oppose that of Wg. Here, we analyze the relevance of this transcriptional reg...

Patterning of the Drosophila embryo depends on the accurate expression of wingless (wg), which encodes a secreted signal required for segmentation and many other processes. Early expression of wg is regulated by the nuclear proteins of the gap and pair-rule gene classes but, after gastrulation, wg transcription is also dependent on cell-cell communication. Signaling to the Wg-producing cells is...

We have expressed the segment polarity gene wingless (wg) ectopically in imaginal discs to examine its regulation of both ventral patterning and transdetermination. By experimentally manipulating the amount of Wg protein, we show that different thresholds of Wg activity elicit different outcomes, which are mediated by regulation of decapentaplegic (dpp) expression and result in alterations in t...