نتایج جستجو برای: zymosan

تعداد نتایج: 1568  

Journal: :iranian journal of immunology 0
ziba ghasemi department of immunology, faculty of medicine, shaheed beheshti university of medical sciences, tehran, iran babak farrokhi department of immunology, faculty of medicine, shaheed beheshti university of medical sciences, tehran, iran farah miraghasi department of immunology, faculty of medicine, shaheed beheshti university of medical sciences, tehran, iran ardalan ejaz ahmad shiraz institute for cancer research, shiraz university of medical sciences, shiraz, iran nariman mosaffa department of immunology, faculty of medicine, shaheed beheshti university of medical sciences, tehran, iran

background: polysaccharides have long been used as immune-modulators in various pathologic conditions including inflammation and solid malignancies. objective: to evaluate the effects of zymosan and betaglucan on cytotoxic reactions in an effectortarget conjugate system. methods: blood was obtained from 20 healthy subjects; purified mononuclear leukocytes (monocytes and lymphocytes) were extrac...

Journal: :Journal of Investigative Dermatology 2022

Cathelicidin LL37 is overexpressed in plaques psoriasis. Microbial ligands are part of the triggers over-expression. [Our objectives were] to assess expression LL37, interleukins 17 and 23 skin ex vivo submitted a microbial ligand, then effects AGH8 (vegetal extract) same model. Human explants were ligand: zymosan A at 1% was applied surface on day 0, D2, D3 D6. topically after removal zymosan-...

Cuong Trinh Tat, Diem Giang Huy Doan Tran Trung Hung Hoang the huy Nguyen Quang Phuong Nguyen

Wedelolactone is known to have biological activities such as anti-inflammation hepatitis, anti-hepatotoxic activity, and trypsin inhibitory effect. However, up to date, there has not been studied deeply in the role of wedelolactone for zymosan-induced signaling pathways in the process of regulating the excessive inflammatory responses in host. Here, we demonstrated that wedelolactone plays an e...

Cuong Trinh Tat, Diem Giang Huy Doan Tran Trung Hung Hoang the huy Nguyen Quang Phuong Nguyen

Wedelolactone is known to have biological activities such as anti-inflammation hepatitis, anti-hepatotoxic activity, and trypsin inhibitory effect. However, up to date, there has not been studied deeply in the role of wedelolactone for zymosan-induced signaling pathways in the process of regulating the excessive inflammatory responses in host. Here, we demonstrated that wedelolactone plays an e...

Ardalan Ejaz Ahmad Babak Farrokhi Farah Miraghasi Nariman Mosaffa, Ziba Ghasemi

Background: Polysaccharides have long been used as immune-modulators in various pathologic conditions including inflammation and solid malignancies. Objective: To evaluate the effects of Zymosan and Betaglucan on cytotoxic reactions in an effectortarget conjugate system. Methods: Blood was obtained from 20 healthy subjects; purified mononuclear leukocytes (monocytes and lymphocytes) were extrac...

Journal: :Journal of Immunology 2021

Abstract HIV reservoirs persist in gut-homing CD4+ T cells of people living with and receiving antiretroviral therapy, but the antigenic specificity such remains poorly documented. The imprinting for gut homing is mediated by retinoic acid (RA), a vitamin A–derived metabolite produced dendritic (DCs) exhibiting RA-synthesizing (RALDH) activity. RALDH activity DCs can be induced TLR2 ligands, as...

Journal: :The Biochemical journal 1992
K Kimura M Shiota K Mochizuki M Ohta T Sugano

Zymosan (non-boiled) induced glycogenolysis biphasically, with no lag time, in the perfused rat liver. After the zymosan was boiled, it could be separated into two fractions, both of which stimulated glycogenolysis independently. The soluble fraction of boiled zymosan (zymosan sup) showed homologous desensitization, indicating that zymosan sup-induced glycogenolysis is a receptor-mediated event...

Journal: :Arthritis & Rheumatism 1977

2018
Jicong Du Pei Zhang Hainan Zhao Suhe Dong Yanyong Yang Jianguo Cui Fu Gao Jianming Cai Cong Liu

It proved that Zymosan-A protected the haematopoietic system from radiation-induced damage via Toll-Like Receptor2 in our previous study. In this study, we investigated the potential mechanism for the radioprotective effects of Zymosan-A. The mice were treated with Zymosan-A (50 mg/kg, dissolved in NS) via peritoneal injection 24 and 2 hours before ionizing radiation. Apoptosis of bone marrow c...

Journal: :Journal of immunology 2009
Maryse Thivierge Jana Stankova Marek Rola-Pleszczynski

TLRs sense microbial products and initiate adaptive immune responses by activating dendritic cells (DCs). DCs have been shown to produce leukotrienes and, conversely, leukotrienes are known to modulate several DC functions. In this study, we examined the modulation of expression and function of cysteinyl-leukotriene receptor type 1 (CysLT1) on human monocyte-derived DCs during their differentia...

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