We study a special case of a structured mixed integer programming model that arises in production planning. For the most general case of the model, called PI, we have earlier identified three families of facet–defining valid inequalities: (l, S) inequalities (introduced for the uncapacitated lot–sizing problem by Barany, Van Roy, and Wolsey), cover inequalities, and reverse cover inequalities. ...

We have identified and characterized a secreted protein, designated Pic, which is encoded on the chromosomes of enteroaggregative Escherichia coli (EAEC) 042 and Shigella flexneri 2457T. The product of the pic gene is synthesized as a 146.5-kDa precursor molecule which is processed at the N and C termini during secretion, allowing the release of a mature protein (109.8 kDa) into the culture sup...

In this letter, adaptive multi-stage parallel interference cancellation (PIC) receiver is considered for multi-rate DS-CDMA system. In each stage of the adaptive multi-stage PIC receiver, multiple access interference (MAI) estimates are obtained by the sub-bit estimates from the previous stage and the adaptive weights for the sub-bit estimates. The adaptive weights are obtained by minimizing th...

Persistent inward current (PIC) plays an important role in setting the input-output gain of motoneurons. In humans, these currents are estimated by calculating the difference between synaptic input at motor unit recruitment and derecruitment (ΔF) derived from paired motor unit recordings. The primary objective of this study was to use the relationship between reciprocal inhibition (RI) and PIC ...

Previous studies in our laboratory have demonstrated that focal injections of picolinic acid (PIC) protect the cholinergic neurons of the nucleus basalis magnocellularis (nbm) against quinolinic acid (QUIN)-induced neurotoxicity. The present study was designed to examine the effects of chronic infusions of QUIN and PIC on nicotinamide adenine dinucleotide (NADPH) diaphorase containing neurons o...