The mid-Pleistocene Transition from 40 ky to ∼100 ky glacial cycles is generally characterized as a singular transition attributable to scouring of continental regolith or a long-term decrease in atmospheric CO2 concentrations. Here an alternative hypothesis is suggested, that Pleistocene glacial variability is chaotic and that transitions from 40 ky to ∼100 ky modes of variability occur sponta...

A pair of fly impressions is described as a new species of a new genus, Orientisargus illecebrosusgen. et sp. n., referred to a new family Orientisargidaefam. n. within Archisargoidea of Brachycera, Diptera. The systematic position of Orientisargidae is discussed. Daohugosargusgen. n. is proposed for Sharasargus eximius KY Zhang et al., 2008. Uranorhagionidae is a junior synonym for Archisargid...

a Department of Chemistry, University of Kentucky, Lexington, KY 40506, USA b Center of Membrane Sciences, University of Kentucky, Lexington, KY 40506, USA c Graduate Center for Toxicology, University of Kentucky, Lexington, KY 40536, USA d Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA e Department of Pathology and Neurology, University of Kentucky, Lexington, ...

KY-62 is a water-soluble analog of amphotericin B. In vitro testing of five clinical isolates of Candida albicans showed KY-62 to have potency similar to that of amphotericin B. KY-62 was administered to mice infected intravenously with C. albicans. In vivo, KY-62 was effective in immunocompetent mice, with potency similar to that of amphotericin B. KY-62 was well tolerated up to 30 mg/kg of bo...

in  this paper, we investigate the generalizedhyers-ulam-rassias stability for the quartic, cubic and additivefunctional equation$$f(x+ky)+f(x-ky)=k^2f(x+y)+k^2f(x-y)+(k^2-1)[k^2f(y)+k^2f(-y)-2f(x)]$$ ($k in mathbb{z}-{0,pm1}$) in $p-$banach spaces.

Lactobacillus rhamnosus KY-3 is a fermentative bacterium that is used for the industrial production of L-lactic acid. We have examined the effect of L. rhamnosus KY-3 and cellobiose as synbiotics on lipid metabolism in rats. Rats were fed on a 20% casein diet (C) supplemented with either 1.7% L. rhamnosus KY-3 (KY-3), 10% cellobiose (CEB), or 1.7% L. rhamnosus KY-3 and 10% cellobiose (KY-3+CEB)...

400. Beyond the Antibiogram: Using Monte Carlo Analysis to Optimize Institution-Specific Antipseudomonal Therapy Sarah Tennant, PharmD; Jeffrey M. Rybak, PharmD; Donna R. Burgess, RPh; David S. Burgess, PharmD, FCCP; Craig Martin, PharmD; University of Kentucky HealthCare, Lexington, KY; University of Kentucky Healthcare, Lexington, KY; University of Kentucky, College of Pharmacy, Lexington, KY...