Background: The risk of atherosclerosis and cancer is high in hemodialysis (HD) patients. There is evidence that HD causes oxidative stress. However, the causative factors of oxidative stress are unknown. It has been suggested that HD imposes an additional oxidative stress on patients with chronic renal failure by activation of granulocytes on dialyzer membranes resulting in an imbalance betwee...

Background: Sinus surgeries are usually associated with bleeding, thus can result in hemodynamic instability. This study investigated the hemodynamic changes induced by remifentanil plus isoflurane administration in comparison with propofol plus remifentanil in patients undergoing sinus surgery.Methods: In this randomized clinical trial study, 96 patients were divided into two groups of isofl...

Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufe...

Background and purpose: Administration of high dose of remifentanil and propofol provides adequate coditions for tracheal intubation without musclerelaxants. Intubating conditions with meperidine, propofol and low doses of remifentanilcompared in this study. Materials and methods: After premedication withmidazolam 0.03 mg/kg and meperidine1mg/kg, 60 patients under orthopedic surgeryrandomized ...

Responses to painful stimulus are associated with broad range of physiological changes in human body. One of these significant responses is an increase in plasma norepinephrine level that may cause different systemic effects like coronary spasm, hypercoagulation, demand/supply ratio imbalance in myocardium, etc. Many clinical trials have tried to eliminate or decrease these changes by ...

Background: Endoscopic procedures are performed for diagnosis and treatment of GI disturbances and require adequate, short-time anesthesia. Propofol is a rather recently introduced IV drug used for its conscious sedation effects. This study has compared the effects and complications of propofol versus midazolam in endoscopic procedures in Hamedan in 2001. Materials and Methods: This double blin...

        Abstract Aim and Background:   This study is aimed to assess the effect of aminophylline (1mg/kg) on reversal of the sedative effects of propofol and the recovery time in patients under propofol anesthesia. Due to the known effects of aminophylline on myocardial contractility and the increase in cardiac outpu...

زمینه و هدف: دکسمدتومیدین به عنوان یک آگونیست آلفا- 2 با اثرسمپاتولیتیک مرکزی، یک بیهوش کننده قوی و ضددرد است که می تواند سبب پایداری وضعیت همودینامیک شود ولی با توجه به اثر بیهو ش کنندگی آن امکان تاخیر در زمان ریکاوری در تجویز انفوزیون آن ناشناخته است. هدف از مطالعه حاضر بررسی تجویز وریدی دکسمدتومیدین بر ریکاوری بیماران تحت جراحی فیوژن خلفی ستون فقرات است. مواد و رو شها: در این مطالعه بیماران ...

Introduction & Objective: By prevention of bleeding during spine surgery, we could provide suitable field for the surgeon and also reduce blood loss and the need for transfusion. The purpose of this study was to compare the effects of intravenous administration of propofol and isoflurane for anesthesia maintenance on the amount of blood loss and hemodynamic status during the surgery. Materials ...