نیتروگلیسیرین در درمان زنان کولیک : یک مطالعه آینده نگر، راندوم، پوشیده مضاعف و کنترل شده

جواد زرگوشی

چکیده

background: organic nitrates relax all kinds of smooth muscle , not only vascular smooth muscle , a fact that has allowed the use of these drugs to treat many different aliments. objective.-the purpuse of this study was to examine prosepectively benefical effects , if any, of sublingual nitroglycerin on the pain of renal colic. design.- prospective , randomised , double blind, placebo- contoled clinical trial of 3 month duration setting .- emergency rooms at 2 university - based hospitals in kermanshah , iran. participants.-from april 5,1992 to july , 1992 one hundred persons aged 16 to 60 yrs with typrical renal colic diagnosed by history, clinical , urinary , and radiologic means , were analysed. intervention.- one hundred patients randomly allocated to receive either sublingual nitroglycerin (n=51) or identical placebo (n=49) . nitroglycerin was admininstrated in a dose of 0/4mg. if pain was not relieved