A Peculiar Case of Splenic Marginal Zone Lymphoma and Review of Literature

نویسندگان

  • Ashok Dinda Sanjay Gandhi Postgraduate Institute of Medical Sciences, Department of Pathology, All India Institute of Medical Sciences, New Delhi
  • Rakesh Pandey Sanjay Gandhi Postgraduate Institute of Medical Sciences, Department of Pathology, All India Institute of Medical Sciences, New Delhi
  • Soniya Nityanand Sanjay Gandhi Postgraduate Institute of Medical Sciences, All India Institute of Medical Sciences, India
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Splenic marginal zone lymphoma.

Splenic marginal zone lymphoma (SMZL) is a specific low-grade small B-cell lymphoma that is incorporated in the World Health Organization classification. Characteristic features are splenomegaly, moderate lymphocytosis with villous morphology, intrasinusoidal pattern of involvement of various organs, especially bone marrow, and relative indolent course. Tumor progression with increase of blasti...

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Splenic marginal zone lymphoma: a literature review of diagnostic and therapeutic challenges

Splenic marginal zone lymphoma (SMZL) is a low-grade B-cell non-Hodgkin's lymphoma characterized by massive splenomegaly, moderate lymphocytosis with or without villous lymphocytes, rare involvement of peripheral lymph nodes and indolent clinical course. As a rare disease, with no randomized prospective trials, there is no standard of care for SMZL so far. Splenectomy has been done for many yea...

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Splenic Marginal Zone Lymphoma with Concurrent Myelofibrosis: A Case Report

Myelofibrosis associated with lymphoid neoplasms is a rare occurrence with the exception of hairy cell leukemia. Its incidence in splenic marginal zone lymphoma, as we report in this article, has only been reported once in the past. We report the case of a 62 year old male with splenic marginal zone lymphoma and concurrent myelofibrosis. The diagnosis of splenic marginal zone lymphoma was achie...

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Surgical management of splenic marginal zone lymphoma.

OBJECTIVES Splenic marginal zone lymphoma (SMZL) is a rare indolent B-cell lymphoma with variable prognosis. As a result, there is sparse knowledge on the role of splenectomy and best management approaches. We aim to explore management strategies and outcomes amongst the cohort of SMZL patients at our centre. METHOD A retrospective review of all splenectomies performed at a tertiary referral ...

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Unusual Course of Splenic Marginal Zone Lymphoma

A 53-year-old woman was diagnosed with splenic marginal zone lymphoma by pathological examination on left submandibular lymph node and bone marrow biopsies and markedly enlarged spleen. Four cycles of Rituximab chemotherapy were given. Seven months after finishing Rituximab chemotherapy, she developed left upper extremity swelling without evidence of deep venous thrombosis. Repeat PET/CT scan d...

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عنوان ژورنال

دوره 10  شماره 3

صفحات  186- 189

تاریخ انتشار 2013-09-01

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