Comparison of Serum Zinc Levels in Children with Epilepsy and Febrile Convulsions
نویسندگان
چکیده مقاله:
Introduction: Epilepsy is one of the most common and chronic neurological diseases in children. The prevalence of this disease among children in Iran is estimated at 5%, which is higher than the average prevalence in other countries. Several studies have been done on the role of trace elements in serum and its role in the pathogenesis of epilepsy, but there is still little information on the role of zinc and its serum level in children with epilepsy compared to fever-induced seizures. Methods: Patients with febrile convulsion and epileptic patientsyounger than 6 years old and admitted to pediatric neurology ward of Ghaem hospital from mordad to azar 1398 were divided into two groups of 22 each with parental consent. The third group was selected as the control group with 22 patients in the same age range from febrile patients without pediatric seizure. The amount of 2 ml of blood was collected within the first 6 hours of admission and measured in the biochemical laboratory of Ghaem Hospital by a dedicated serum zinc expert. At the end the results were compared and then analyzed. Results: A total of 22 epileptic children, 22 children with febrile seizure and 22 children with no seizure as control group were enrolled. The mean age of the patients in the study was 3.00±1.84. The results showed that the serum zinc level in the group of children with epilepsy was 84.53±29.42mg.L, in the febrile seizure group was 82.14±27.61mg.L and in the control group was 83.02±28.25mg.L. Results of statistical analysis showed that there was no significant difference between the three groups (P = 0.96). Statistical analysis also showed no significant difference between each two groups. Conclusions: The results of this study show that there is no difference between serum zinc level between patients with febrile convulsion and those with epilepsy. However, according to the results of other studies, further studies with larger sample sizes are needed to obtain stronger evidence in this topic.
منابع مشابه
Serum zinc and copper levels in children with febrile convulsion
Febrile convulsions (FC) are the most common neurologic disorder in children 6-60 months of age. Zinc (Zn) and copper (Cu) play role as cofactors in more than 300 enzymatic activities significantly. The aim of this study was to evaluate the relationship serum levels of Zn and Cu with seizure occurrence in febrile children. In this case-control study, 270 children with 6 month to 6 years were ev...
متن کاملSerum Zinc Level in Children With Simple Febrile Convulsions
Implication for health policy/practice/research/medical education: Febrile convulsions are the most common convulsive seizures in infants and preschool children. They are a leading cause of parental anxiety and family disruption. Recent studies have shown low serum zinc levels in children with febrile convulsions. Therefore, we carried out a study to determine and compare the serum zinc level i...
متن کاملAssessment of the Relation between Serum Zinc & magnesium Levels in Children with Febrile Convulsion
Background and Objectives: Febrile convulsion is one of the most common types of seizure in childhood. Its pathogenesis is unknown, so studying its cause is valuable. The purpose of this study was to determine the serum level of zinc and magnesium in children withfebrileconvulsion (F.C) (3 months to 6 years age). Patients and Methods: In this analytical case-control study, serum le...
متن کاملcomparison of serum zinc and copper levels in children and adolescents with intractable and controlled epilepsy
how to cite this article: kheradmand z, yarali b, zare a, pourpak z, shams s, ashrafi mr. comparison of serum zinc and copper levels in children and adolescents with intractable and controlled epilepsy. iran j child neurol. 2014; 8(3):49-54. abstract objective trace elements such as zinc and copper have physiological effects on neuronal excitability that may play a role in the etiology of int...
متن کاملserum zinc and copper levels in children with febrile convulsion
febrile convulsions (fc) are the most common neurologic disorder in children 6-60 months of age. zinc (zn) and copper (cu) play role as cofactors in more than 300 enzymatic activities significantly. the aim of this study was to evaluate the relationship serum levels of zn and cu with seizure occurrence in febrile children. in this case-control study, 270 children with 6 month to 6 years were ev...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 13 شماره None
صفحات 123- 130
تاریخ انتشار 2021-12
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
کلمات کلیدی برای این مقاله ارائه نشده است
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023