Stromal Cell Derived Factor-1 Genetic Variation at Locus 801 in Patients with Myasthenia Gravis

stromal cell derived factor-1 genetic variation at locus 801 in patients with myasthenia gravis

background: myasthenia gravis (mg) is the most common disorder of neuromuscular junction in which autoantibodies develop against nicotinic acetylcholine receptor for unknown reasons. the association of immunomodulator genes with different autoimmune disease has been studied in recent years. objective: the aim of this study was to investigate correlation between a genetic variation in stromal ce...

Thymectomy in Patients with Myasthenia Gravis

A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative pre­paration, anesthetic and surgical management is -discussed. 

Genetic associations in myasthenia gravis

Genetic study of sample of 70 patients with myasthenia gravis.

The role of genetic factors in the causation of myasthenia gravis is not clear. Oppenheim, as early as 1900, reported familial instances of myasthenia and suggested that genetic factors were involved. On the other hand, Ford in 1937 stated, 'there is never any familial or hereditary tendency in myasthenia gravis'. However, since then, there have been several reports of familial instances of mya...

Association between myasthenia gravis and HLA antigens in patients

Introduction: Myasthenia gravis is a disease of neuromuscular junction. Familial cases have been reported. Relation between myasthenia gravis and HLA antigens has been seen in many studies from different parts of the world. The aim of this study is determination of association between HLA class I haplotypes and myasthenia gravis in Kerman province. Methods: In this cross sectional study 44 my...

Demyelinating disease in patients with myasthenia gravis.

Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented dist...