The Role of Arginine-Phenylalanine-Amide-Related Peptides in Mammalian Reproduction

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چکیده مقاله:

Until 2000 it was believed that gonadotropin-releasing hormone (GnRH) was the sole regulator of hypophyseal gonadotropes. In 2000, the discovery of a gonadotropin inhibitory hormone (GnIH) initiated a revolution in the field of reproductive physiology. Identification of GnIH homologues in mammals, the arginine-phenylalanine- amide (RFamide)-related peptides (RFRPs), indicated a similar function. Subsequently, further works conducted in various laboratories worldwide have shown that these neuropeptides inhibit the hypothalamic-hypophyseal axis. This review discusses the role of RFRPs in mammalian reproductive processes.

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the role of arginine-phenylalanine-amide-related peptides in mammalian reproduction

until 2000 it was believed that gonadotropin-releasing hormone (gnrh) was the sole regulator of hypophyseal gonadotropes. in 2000, the discovery of a gonadotropin inhibitory hormone (gnih) initiated a revolution in the field of reproductive physiology. identification of gnih homologues in mammals, the arginine-phenylalanine- amide (rfamide)-related peptides (rfrps), indicated a similar function...

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The Role of Arginine-Phenylalanine-Amide-Related Peptides in Mammalian Reproduction

Until 2000 it was believed that gonadotropin-releasing hormone (GnRH) was the sole regulator of hypophyseal gonadotropes. In 2000, the discovery of a gonadotropin inhibitory hormone (GnIH) initiated a revolution in the field of reproductive physiology. Identification of GnIH homologues in mammals, the arginine-phenylalanine-amide (RFamide)-related peptides (RFRPs), indicated a similar function....

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Is precocious puberty linked to hypothalamic expression of arginine-phenylalanine-amide-related peptide?

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عنوان ژورنال

دوره 9  شماره 3

صفحات  268- 276

تاریخ انتشار 2015-10-01

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