Rheumatoid arthritis is an inflammatory autoimmune condition, and tumor necrosis factor-α (TNF-α) plays an important role in its pathophysiology. In vitro, (E)-N'-(3,4-dimethoxybenzylidene)-N-methylbenzohydrazide (LASSBio-1359) has exhibited anti-TNF-α properties, and in vivo these effects are mediated via activation of adenosine receptor. This work investigates the antinociceptive action of LA...

Women at high risk of developing breast cancer are prescribed selective estrogen response modulators, including raloxifene, as chemoprevention. Patients often seek complementary and alternative treatment modalities, including herbal products, to supplement prescribed medications. Milk thistle preparations, including silibinin and silymarin, are top-selling herbal products that may be consumed b...

Officers and other representatives of more than a dozen food-, nutrition-, and health-related scientific societies and organizations, food industry scientists, and staff of the USDA, the CDC, the Food and Drug Administration, and the NIH convened on 8 December 2014 in Washington, DC, to reach a consensus among individuals participating on guiding principles for the development of research-orien...

We show that a class of microeconomic behavioral models with interacting agents, introduced by Kirman (1991, 1993), can replicate the empirical long-memory properties of the two rst conditional moments of nancial time series. The essence of these models is that the forecasts and thus the desired trades of the individuals in the markets are in uenced, directly, or indirectly by those of the othe...

Pges 17–1920 FEATURE ARTICLE Li-Wen Xu, Jie Luo and Yixin Lu Asymmetric catalysis with chiral primary amine-based organocatalysts ISSN 1359-7345 COMMUNICATION Ruizhi Wu, Talal F. Al-Azemi and Kirpal S. Bisht Spatially directional multiarm poly(ε-caprolactone) based on resorcin[4]arene cavitand core 1359-7345(2009)14;1-2 www.rsc.org/chemcomm Number 14 | 14 April 2009 | Pages 1781–1920 Chemical C...

OBJECTIVE Evaluate the prevalence of aortic arch anatomy and branching pattern variants and anomalies in 1359 patients by Multi-Detector Computed Tomography Angiography. METHODS Retrospective multi-centric study including exams performed for various clinical issues with the same acquisition and injection protocols on 64-slices scanners. Multi-Planar reformations and Volume Rendering Images we...

In this article, we accomplish two things. First, we show that despite empirical psychologists’ nominal endorsement of a low rate of false-positive findings (≤ .05), flexibility in data collection, analysis, and reporting dramatically increases actual false-positive rates. In many cases, a researcher is more likely to falsely find evidence that an effect exists than to correctly find evidence t...

The effects of a major storm event (Hurricane Gordon) on the biogeochemistry of Atlantic coastal and Gulf Stream waters were investigated during a research cruise in November 1994. Prestorm, NH , NO , and PO 1 2 23 4 3 4 concentrations were consistently well below 1 mM, whereas after the storm, nutrient concentrations were higher in the surface-water samples: .2 mM, in some instances. Primary a...

Norbert Hofmann (Bearb.), Archiv der Freiherren von Woellwarth: Urkundenregesten 1359-1840 (Inventare nichtstaatlichen Archive in Baden-Württemberg, Bd. 19), Stuttgart (Kohlhammer) 1991. 359 S.