Mucormycosis is an emerging fungal infection that is clinically difficult to manage, with increasing incidence and extremely high mortality rates. Individualswith diabetes, suppressed immunity or traumatic injuryare at increased risk of developing disease. These individuals often present with defects in phagocytic effector cell function. Research using mammalian models and phagocytic effector c...

The current study examined the bioactivation potential of ghrelin receptor inverse agonists, 1-{2-[2-chloro-4-(2H-1,2,3-triazol-2-yl)benzyl]2,7-diazaspiro[3.5]nonan-7-yl}-2-(imidazo[2,1-b]thiazol-6yl)ethanone (1) and 1-{2-[2-chloro-4-(2H-1,2,3-triazol-2-yl)benzyl]-2,7diazaspiro[3.5]nonan-7-yl}-2-(2-methylimidazo[2,1-b]thiazol-6-yl) ethanone (2), containing a fused imidazo[2,1-b]thiazole motif i...

Tryptophan metabolites have been linked in observational studies with type 2 diabetes, cognitive disorders, inflammation and immune system regulation. A rate-limiting enzyme in tryptophan conversion is arylformamidase (Afmid), and a double knockout of this gene and thymidine kinase (Tk) has been reported to cause renal failure and abnormal immune system regulation. In order to further investiga...

M. Jardak,a ∗I. M. Navon b and M. Zupanski c a Laboratoire de Métórologie Dynamique/CNRS École Normale Supérieure, Paris, France b Department of Scientific Computing, Florida State University, Tallahassee, FL 32306-4120, USA c Cooperative Institute for Research in the Atmosphere, Colorado State University, 1375 Campus Deliver, Fort Collins, CO 80523-1375, USA ∗Correspondence to: M.Jardak, Labor...

Blum, R. H., Raemer, D. B., Carroll, J. S., Dufresne, R. L., & Cooper, J. B. (2005). A method for measuring the effectiveness of simulation-based team training for improving communication skills. Anesthesia & Analgesia, 100(5), 1375-1375-1380. Team behavior and coordination, particularly communication or team information-sharing, are critical for optimizing team performance. This study develope...

The viscosity of slag from an operating integrated gasification combined cycle (IGCC) plant utilising petroleum coke and a synthetic petcoke with the same composition made chemical grade oxides in reducing environment for application were investigated this study. A high temperature rotating bob-type viscometer was used to measure between temperatures 1250–1375 °C. Natural ash had similar viscos...

Scientific writing is a general label with a great deal of variation at any period. Empirical evidence of variation within genres of the early periods has been produced by studies of the Helsinki Corpus of English Texts, as they have shown that umbrella categories like ‘religious treatises’ or ‘scientific writing’ contain very heterogeneous texts (Meurman-Solin 1993, Taavitsainen 1993, 1994a). ...