نتایج جستجو برای: c13

تعداد نتایج: 1233  

C13

Journal: :Arthropod Management Tests 2012

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2011

Journal: :Tetrahedron letters 2013
Alec Saitman Steven D E Sullivan Emmanuel A Theodorakis

An efficient strategy for the construction of C13-oxidized cembrenolides is reported. Central to this strategy is the installation of the C13 hydroxyl group prior to cembrane macrocyclization (via formation of the C1-C2 bond), allowing access to both C13 alcohol epimers. The orientation of the C13 alcohol was found to influence the cyclization mode of the cembranolide scaffold upon furan oxidat...

Journal: :Journal of cancer therapy 2011
Cody P Coyne Toni Jones Andrzej Sygula John Bailey Lesya Pinchuk

PURPOSE Discover the anti-neoplastic efficacy of epirubicin-(C13-imino)-[anti-HER2/neu] against chemotherapeutic-resistant SKBr-3 mammary carcinoma and delineate the capacity of selenium to enhance it's cytotoxic anti-neoplastic potency. METHODS In molar excess, EMCH was combined with epirubicin to create a covalent epirubicin-(C13-imino)-EMCH-maleimide intermediate with sulfhydryl-reactive p...

Journal: :The Journal of Experimental Medicine 1985
A Yamada J F Young F A Ennis

We have tested the ability of the c13 protein, which is a hybrid protein of the first 81 amino acids of the viral nonstructural protein (NS1) and the HA2 subunit of viral hemagglutination produced in E. coli, to render target cells susceptible to the lytic activity of influenza virus-specific cytotoxic T lymphocytes (CTL). The results showed that P815 cells coated with c13 protein were lysed by...

Journal: :Reproductive BioMedicine Online 2010

Journal: :The Journal of Experimental Medicine 1985
A Yamada M R Ziese J F Young Y K Yamada F A Ennis

We have tested the abilities of various polypeptides of A/PR/8/34 (H1N1) virus, constructed by recombinant DNA techniques, to induce influenza virus-specific secondary cytotoxic T lymphocyte (CTL) responses. A hybrid protein (c13 protein), consisting of the first 81 amino acids of viral nonstructural protein (NS1) and the HA2 subunit of viral hemagglutinin (HA), induced H-2-restricted, influenz...

Journal: :Oncology reports 2006
Masanori Hirama Seiji Isonishi Makoto Yasuda Hiroshi Ishikawa

One of the mechanisms of cisplatin cell cytotoxicity is the mitochondria-associated induction of apoptosis. The morphological or functional change of mitochondria in cisplatin-resistant cells has already been reported. Herein we present additional data describing the mitochondrial genomic and functional changes in cisplatin- resistant cells. Cisplatin increased the level of apoptotic cells in c...

Journal: :Physical Review C 2017

2006
Karen Zinkewich-Péotti Paul A. Andrews Karen Zinkewich-Peotti

Cisplatin (DDP)-resistant 2008 human ovarian carcinoma cells (C13*) have an elevated mitochondria! membrane potential that confers hypersensitivity to lipophilic cations. We have addressed whether this change was directly linked to the DDP-resistant phenotype or was a random alteration, unrelated to resistance. The elevated mitochondria! membrane potential and ensuing rhodamine 123 (Rhl23) hype...

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