Drug combinations have been known to be used either for increasing effcctivity or for decreasing side-efFects. It is only when multiple drugs are prescribed without adequate scientific evidence in their favour then such practices need careful scrutiny. Multiple drug use in psychiatry has recently gained currency and so require thoughtful consideration. The term polypharmacy is generally used to...

Patients with impaired immunity are at particular risk of infections with Candida albicans. Antifungal drugs such as azoles commonly used for candidiasis treatment, but drug resistance is one of the most common problems for public health. The aim of this study was to evaluate the expression of lanosterol 14-demethylase (ERG11) gene for three-drug combinations in C. albicans. Disk diffusion and ...