Background: To study the morphological development and histomorphometry of foetal and adult ovaries in Kano brown goats. Materials and Methods: Fifty-one foetal and fourteen adult ovaries obtained from slaughtered Kano brown does in Nsukka abattoir were used for this study. The ages of the adult does were determined by dentition and foetuses by crown rump length method. The foetal and adult ova...

Foetal movements commence at seven weeks of gestation, with the foetal movement repertoire including twitches, whole body movements, stretches, isolated limb movements, breathing movements, head and neck movements, jaw movements (including yawning, sucking and swallowing) and hiccups by ten weeks of gestational age. There are two key biomechanical aspects to gross foetal movements; the first be...

Differentiated derivatives of human pluripotent stem cells (hPSCs) are often considered immature because they resemble foetal cells more than adult, with hPSC-derived cardiomyocytes (hPSC-CMs) being no exception. Many functional features of these cardiomyocytes, such as their cell morphology, electrophysiological characteristics, sarcomere organization and contraction force, are underdeveloped ...

Alternative splicing (AS) drives determinative changes during mouse heart development. Recent high-throughput technological advancements have facilitated genome-wide AS, while its analysis in human foetal heart transition to the adult stage has not been reported. Here, we present a high-resolution global analysis of AS transitions between human foetal and adult hearts. RNA-sequencing data showe...

Rat brown adipocytes at day 22 of foetal development showed greater size, higher mitochondria content and larger amounts of lipids, as determined by flow cytometry, than 20-day foetal cells. Simultaneously, an inhibition on the percentage of brown adipocytes into S+G2/M phases of the cell cycle was observed between days 20 and 22 of foetal development. The expression of several adipogenesis-rel...

In the present study, we aimed to gather morphometric data on the localisation and development of the pancreas during the foetal period. The study was carried out on 222 human foetuses aged 9-40 weeks of gestation with no external pathology or anomaly. The abdominal wall was dissected after general external measurements of the foetuses were carried out. Data on the localisation of the pancreas ...

INTRODUCTION AND OBJECTIVE The growing epidemic of childhood obesity has forced scientists to search for methods to prevent feeding disorders. Increasing interest in appetite regulating hormones has revealed their influence on energy homeostasis after birth or even in utero. STATE OF KNOWLEDGE The presence of ghrelin in the stomach of human foetuses and the distinctive production in the pancr...

1. Premature delivery of foetal rats by uterine section results in the rapid appearance of tyrosine aminotransferase activity in foetal liver, after an initial lag period of 3-6hr. 2. The premature induction of activity is completely repressible by actinomycin D given soon after delivery and partially repressible by puromycin and amino acid analogues. 3. Glucagon injections into foetal rats in ...