Background: Glial fibrillaryacidic protein (GFAP), an intermediate filament protein, is mainly expressed by astrocytes, but some other cells like enteric glia and non-myelinating Schwann cells can also express GFAP. GFAP elevation has been reported in some types of meningioma and malignant brain tumors. In the present study, we analyzed the association between serum levels of GFAP with meningio...

Meningioma is considered as a benign central nervous system tumor that accounts for approximately 18% of all brain tumors. About 5% of meningioma tumors are malignant and have more aggressive clinical signs and worse prognosis compared to benign tumors. Extracranial metastasis of meningioma is rare but in the case of occurrence, it is more prevalent in lung, liver and lymph nodes. Osseous metas...

conclusions primary extracranial meningiomas (pems) without intracranial origin are very rare and because of their slow growing nature are initially managed by primary care physicians. case presentation we report a case of slowly progressing extracranial meningioma that was presented in a young adult woman. the tumor was asymptomatic but large enough to cause cosmetic discomfort. patient underw...

meningioma is usually a benign central nervous system (cns) tumor. metastasis is rare; however if it does occur the most metastatic sites are the liver and lungs. here, two cases of cns meningioma with metastasis to cervical lymph nodes are reported. the first case, a 48 year-old man developed cervical lymph node metastasis nine years after primary tumor diagnosis. the second case, a 23 year-ol...

OBJECTIVE To investigate the potential involvements of E-cadherin and beta-catenin in meningioma. METHODS Immunohistochemistry staining was performed on samples from patients with meningioma. The results were graded according to the positive ratio and intensity of tissue immunoreactivity. The expression of E-cadherin and beta-catenin in meningioma was analyzed by its relationship with WHO2007...

Meningioma is a common pathology in the central nervous system (CNS). It arises from the arachnoid cap cells of the arachnoid villi in the meninges, which envelop the brain and spinal cord. Therefore, a meningioma can occur anywhere from the vertex to the spine. It is often named according to its anatomical location. For example, a meningioma abutting the sphenoid bone between the frontal and t...

Cystic meningioma is a rare form of intracranial meningioma. Meningiomas are typically solid tumors but may rarely have cystic components. The diagnosis of cystic meningioma is clinically challenging as the finding of multiple intra-axial tumors, including metastatic tumors, is relatively common. We report a case of cystic meningioma initially diagnosed as a metastatic tumor from a recurrence o...

Primary ectopic meningiomas are extremely rare tumors of controversial origin and they are usually limited to the head and neck region. Its occurrence at the mediastinum is even rarer. There has not been any official report regarding primary mediastinal malignant meningioma until today. Because of its rarity and potential value, we report here a case of primary mediastinal malignant meningioma,...