An Efficient Protocol for the Synthesis of Carboacyclic Nucleosides via Aza-Conjugate Addition Reaction
نویسندگان
چکیده مقاله:
A new efficient method for the synthesis of carboacyclic nucleosides as biologically interesting compounds via aza-conjugate addition of pyrimidine nucleobases to a,β-unsaturated esters in the presence of catalytic amount of LiOH.H2O (1.2-4.8 mol%) under microwave irradiation is described. This method affords the title compounds in good to excellent yields and in short reaction times.
منابع مشابه
an efficient protocol for the synthesis of carboacyclic nucleosides via aza-conjugate addition reaction
a new efficient method for the synthesis of carboacyclic nucleosides as biologically interesting compounds via aza-conjugate addition of pyrimidine nucleobases to a,β-unsaturated esters in the presence of catalytic amount of lioh.h2o (1.2-4.8 mol%) under microwave irradiation is described. this method affords the title compounds in good to excellent yields and in short reaction times.
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عنوان ژورنال
دوره 29 شماره 4
صفحات 67- 73
تاریخ انتشار 2010-12-01
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