Determination of frequency the non-immune to rubella in 14-18 years old girls in rafsanjan city 1379

 Background and objective: Congenital Rubella Syndrom (CSR) could be  prevented if young women knew their immune status befor pregnancy,contributing in this way to decrease the birth morbidity rate due to CRS amonge the children.  Method: In order to determination the level of antibody or immunity to rubella in  rafsanjan city,270 sera of 14-18 years old girls were evaluated reterospectivly.ELISA method used for detection of IgG Antibody against rubella virus. Finding: from 270 cases that contributed in this study, 19 cases (7.1%) were nonimmune and 251 (92.9%) were immune according to this method. None of the people in the study had the history of rubella vaccination. The average of antibody concentration in age groups 14, 15, 16, 17 and 18 was respectively 264.8, 209.25, 241.25, 214.13 and 148.17 (Iu/ml). Except the 15 year olds, in the other groups with rasing of age the antibody also rises. Conclusion: Due to lack of past vaccination history, it was conducted that the immunity acquisition was in natural route. It could be due prevalance Rubella infection in the Rafsanjan city.    Key Words: rubella,immunity, Antibody, Young Women