Plasma levels of vascular endothelial growth factor and its soluble receptor in non-alcoholic fatty liver disease
نویسندگان
چکیده مقاله:
Introduction: Non-alcoholic fatty liver disease (NAFLD) is a clinical pathologic condition, which leads to inflammation events in hepatocytes. The objective of present study was to compare the plasma levels of VEGF and sVEGFR-1 as inflammation factors in overweight and obese children and adolescents with and without NAFLD. Materials and Methods: A total sample of 70 overweight and obese children and adolescents (37 boys and 33 girls) were recruited from those admitted to a nutrition clinic in Mashhad, northeastern Iran. The presence of NAFLD was determined by FibroScan, ultrasound and elevation of liver enzyme. Plasma VEGF and sVEGFR1 were also determined for each individual. Results: VEGF levels (log transformed) showed a significant stepwise increase from “zero” to “first”, “second” and “third” grades (P trend
منابع مشابه
Serum levels of vascular endothelial growth factor in non-alcoholic fatty liver disease
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عنوان ژورنال
دوره 6 شماره 2
صفحات 107- 114
تاریخ انتشار 2018-12-16
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