Amir Hossein Mansourabadi

Department of Immunology, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran

[ 1 ] - The role of vitamin D3 and vitamin B9 (Folic acid) in immune system

Background and aims: Vitamins are essential constituents of our diet that Longley have been known to influence the immune system. Vitamin D3 and B9 have received particular attention in recent years as these vitamins have been shown to have an unexpected and crucial effect on the immune response. 1, 25(OH)2D3 metabolizing enzymes and vitamin D r...

[ 2 ] - The role of T helper 9(Th9) against Infectious Diseases

Background and aims: Infectious diseases are disorders caused by organisms such as bacteria, viruses, fungi or parasites .The Th9 subset develops in response to combined signals from TGF-b and IL-4 among a cacophony of other cytokines in an extracellular milieu. T helper 9 (Th9) cells,  as a novel CD4 T cell subset, seem to play a complex role in the outcome of specific immune responses. In thi...

[ 3 ] - The Role of Interleukin (IL-22) in immune response to human diseases

Background and aims: IL-22 is an alpha- helical cytokine. IL-22 binds to a heterodimeric cell surface receptor composed of IL-10R2 and IL-22R1subunits. IL-22R is expressed on tissue cells, and it is absent on immune cells. L-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses. The aim of this study was to i...

[ 4 ] - تاثیر عصاره هیدروالکلی کاکوتی کوهی (Ziziphora clinopodioides Lam) بر تعداد سلول‎های فعال بتای پانکراس در موشهای سوری دیابتی نوع یک ناشی از استرپتوزوتوسین

Background: Diabetes is a metabolic disorder caused by insufficient production of insulin or insulin receptors deficiency. It is now the major cause of morbidity and hospitalization in patients with a significant financial burden to the society. The aim of this study was to evaluate the effect of Ziziphora ethanolic extract on active pancreatic beta cells on streptozotocin induced diabetic mice...